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GATA3 antibody (AA 175-388)

GATA3 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1A10D1 unconjugated
Catalog No. ABIN969167
  • Target See all GATA3 Antibodies
    GATA3 (GATA Binding Protein 3 (GATA3))
    Binding Specificity
    • 40
    • 16
    • 15
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 175-388
    Reactivity
    • 126
    • 97
    • 16
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    Human
    Host
    • 118
    • 28
    • 2
    • 1
    Mouse
    Clonality
    • 108
    • 41
    Monoclonal
    Conjugate
    • 72
    • 10
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    This GATA3 antibody is un-conjugated
    Application
    • 95
    • 48
    • 27
    • 27
    • 26
    • 20
    • 19
    • 16
    • 11
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogen
    Purified recombinant fragment of GATA3 (aa175-388) expressed in E. coli.
    Clone
    1A10D1
    Isotype
    IgG1
    Top Product
    Discover our top product GATA3 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Gulbinas, Berberat, Dambrauskas, Giese, Giese, Autschbach, Kleeff, Meuer, Büchler, Friess: "Aberrant gata-3 expression in human pancreatic cancer." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 54, Issue 2, pp. 161-9, (2006) (PubMed).

    Erpenbeck, Hagenberg, Krentel, Discher, Braun, Hohlfeld, Krug: "Regulation of GATA-3, c-maf and T-bet mRNA expression in bronchoalveolar lavage cells and bronchial biopsies after segmental allergen challenge." in: International archives of allergy and immunology, Vol. 139, Issue 4, pp. 306-16, (2006) (PubMed).

    Mehra, Varambally, Ding, Shen, Sabel, Ghosh, Chinnaiyan, Kleer: "Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis." in: Cancer research, Vol. 65, Issue 24, pp. 11259-64, (2005) (PubMed).

    Jiang: "Development of a new biotic index to assess freshwater pollution." in: Environmental pollution (Barking, Essex : 1987), Vol. 139, Issue 2, pp. 306-17, (2005) (PubMed).

  • Target
    GATA3 (GATA Binding Protein 3 (GATA3))
    Alternative Name
    GATA3 (GATA3 Products)
    Synonyms
    HDR antibody, HDRS antibody, Gata-3 antibody, jal antibody, cb550 antibody, gta3 antibody, GATA-3 antibody, XGATA3 antibody, xgata-3 antibody, hdr antibody, xGATA-3 antibody, GATA3 antibody, GATA transcription factor 3 antibody, T4L20.260 antibody, T4L20_260 antibody, gata3 antibody, ZH-DR antibody, zgc:103531 antibody, GATA binding protein 3 antibody, GATA binding protein 3 S homeolog antibody, GATA transcription factor 3 antibody, amidase antibody, putative amidase antibody, GATA-binding protein 3 antibody, hematopoietic death receptor antibody, GATA3 antibody, Gata3 antibody, gata3 antibody, gata3.S antibody, gatA3 antibody, hdr antibody
    Background

    Description: GATA3: GATA binding protein 3. The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells, macrophages, or HeLa cell lines. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. Labastie et al. (1994) cloned the human gene and the 5-prime end of the mouse gene. The human gene comprises 6 exons distributed over 17 kb of DNA. Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1,but no other structural homologies between the 2 genes could be found.

    Aliases: HDR

    Gene ID
    2625
    HGNC
    2625
    Pathways
    Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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