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GSTM1 antibody

GSTM1 Reactivity: Human, Rat WB, IHC, ELISA, FACS Host: Mouse Monoclonal 1H4F2 unconjugated
Catalog No. ABIN969181
  • Target See all GSTM1 Antibodies
    GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))
    Reactivity
    • 51
    • 34
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 60
    • 12
    • 1
    • 1
    Mouse
    Clonality
    • 61
    • 12
    Monoclonal
    Conjugate
    • 41
    • 13
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    This GSTM1 antibody is un-conjugated
    Application
    • 60
    • 32
    • 30
    • 11
    • 10
    • 9
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human GSTM1 expressed in E. coli.
    Clone
    1H4F2
    Isotype
    IgG1
    Top Product
    Discover our top product GSTM1 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Navarro, Peterson, Chen, Makar, Schwarz, King, Li, Li, Kestin, Lampe: "Cruciferous vegetable feeding alters UGT1A1 activity: diet- and genotype-dependent changes in serum bilirubin in a controlled feeding trial." in: Cancer prevention research (Philadelphia, Pa.), Vol. 2, Issue 4, pp. 345-52, (2009) (PubMed).

  • Target
    GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))
    Alternative Name
    GSTM1 (GSTM1 Products)
    Synonyms
    GST1 antibody, GSTM1-1 antibody, GSTM1a-1a antibody, GSTM1b-1b antibody, GTH4 antibody, GTM1 antibody, H-B antibody, MU antibody, MU-1 antibody, GSTA3 antibody, Gstb-1 antibody, Gstb1 antibody, gst-mu antibody, gst1 antibody, gstm1 antibody, gstm2 antibody, gth4 antibody, gtm1 antibody, glutathione S-transferase mu 1 antibody, glutathione S-transferase M1 antibody, glutathione S-transferase, mu 1 antibody, glutathione S-transferase Mu 1 antibody, glutathione S-transferase mu 2 (muscle) antibody, glutathione S-transferase mu 1 L homeolog antibody, GSTM1 antibody, Gstm1 antibody, LOC100356307 antibody, GSTM2 antibody, LOC100731426 antibody, gstm1.L antibody
    Background

    Description: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

    Aliases: MU, H-B, GST1, GTH4, GTM1, MU-1, GSTM1-1, MGC26563, GSTM1a-1a, GSTM1b-1b

    Molecular Weight
    26 kDa
    Gene ID
    2944
    HGNC
    2944
    Pathways
    Negative Regulation of Transporter Activity
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