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ICAM1 antibody (AA 28-480)

ICAM1 Reactivity: Human ELISA Host: Mouse Monoclonal 6G12 unconjugated
Catalog No. ABIN969206
  • Target See all ICAM1 Antibodies
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Binding Specificity
    • 23
    • 10
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-480
    Reactivity
    • 182
    • 41
    • 22
    • 10
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Human
    Host
    • 113
    • 89
    • 22
    • 3
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 137
    • 90
    • 1
    Monoclonal
    Conjugate
    • 118
    • 23
    • 19
    • 16
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ICAM1 antibody is un-conjugated
    Application
    • 132
    • 115
    • 58
    • 58
    • 45
    • 28
    • 28
    • 25
    • 24
    • 19
    • 15
    • 14
    • 12
    • 10
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA
    Purpose
    ICAM1 Antibody
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human ICAM1(28-480aa) expressed in E. Coli.
    Clone
    6G12
    Isotype
    IgG1
    Top Product
    Discover our top product ICAM1 Primary Antibody
  • Application Notes
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Yang, Cullen, Li, Chapman, Jewell: "Susceptibility to primary sclerosing cholangitis is associated with polymorphisms of intercellular adhesion molecule-1." in: Journal of hepatology, Vol. 40, Issue 3, pp. 375-9, (2004) (PubMed).

  • Target
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Alternative Name
    ICAM1 (ICAM1 Products)
    Background
    ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.
    Molecular Weight
    57.8 kDa
    Gene ID
    3383
    UniProt
    P05362
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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