ITK antibody
(2 references)-
- Target See all ITK Antibodies
- ITK (IL2-Inducible T-Cell Kinase (ITK))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ITK antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Purpose
- ITK Antibody
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human ITK expressed in E. Coli.
- Clone
- 5G6
- Isotype
- IgG1
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anti-IL2-Inducible T-Cell Kinase (ITK) (Internal Region) antibody
Verified ITK Reactivity: Human, Rat WB, ELISA, IHC, FACS, IF Host: Goat Polyclonal unconjugated
anti-IL2-Inducible T-Cell Kinase (ITK) (C-Term) antibodyVerified ITK Reactivity: Human WB, ELISA, IF Host: Goat Polyclonal unconjugated
anti-IL2-Inducible T-Cell Kinase (ITK) (AA 2-110) antibodyITK Reactivity: Human ELISA Host: Mouse Monoclonal 5G12C4 unconjugated
anti-IL2-Inducible T-Cell Kinase (ITK) (pTyr512) antibodyITK Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-IL2-Inducible T-Cell Kinase (ITK) (AA 368-625) antibodyITK Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-IL2-Inducible T-Cell Kinase (ITK) antibodyITK Reactivity: Human ELISA, IHC Host: Rabbit Monoclonal 8F10 unconjugated Recombinant Antibody
anti-IL2-Inducible T-Cell Kinase (ITK) (AA 156-190), (N-Term) antibodyITK Reactivity: Mouse WB Host: Rabbit Polyclonal RB50676 unconjugated
anti-IL2-Inducible T-Cell Kinase (ITK) (AA 25-54), (N-Term) antibodyITK Reactivity: Human WB Host: Rabbit Polyclonal RB37580 unconjugated
anti-IL2-Inducible T-Cell Kinase (ITK) antibodyITK Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-IL2-Inducible T-Cell Kinase (ITK) (AA 169-198) antibodyITK Reactivity: Human WB Host: Rabbit Polyclonal RB03244 unconjugated
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).
: "Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells." in: Molecules and cells, Vol. 28, Issue 2, pp. 125-30, (2009) (PubMed).
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: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).
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- Target
- ITK (IL2-Inducible T-Cell Kinase (ITK))
- Alternative Name
- ITK (ITK Products)
- Background
- This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.
- Molecular Weight
- 72 kDa
- UniProt
- Q08881
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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