KLHL21 antibody

Catalog No. ABIN969246

Cited in 2+ publications. The Mouse Monoclonal anti-KLHL21 antibody (Clone 2H4) (ABIN969246) specifically detects KLHL21 in ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for KLHL21 antibody (ABIN969246)

Target: KLHL21 (Kelch-Like 21 (KLHL21))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLHL21 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Clone: 2H4

Product Details anti-KLHL21 Antibody

Purpose: KLHL21 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human KLHL21 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-KLHL21 antibody (ABIN969246)

Maerki, Olma, Staubli, Steigemann, Gerlich, Quadroni, Sumara, Peter: "The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis." in: The Journal of cell biology, Vol. 187, Issue 6, pp. 791-800, (2009) (PubMed).

Otsuki, Ota, Nishikawa, Hayashi, Suzuki, Yamamoto, Wakamatsu, Kimura, Sakamoto, Hatano, Kawai, Ishii, Saito, Kojima, Sugiyama, Ono, Okano, Yoshikawa, Aotsuka, Sasaki, Hattori, Okumura, Nagai, Sugano et al.: "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. ..." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 12, Issue 2, pp. 117-26, (2005) (PubMed).

Target Details for KLHL21

Target: KLHL21 (Kelch-Like 21 (KLHL21))

Alternative Name: KLHL21

Background: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Molecular Weight: 66 kDa

UniProt: Q9UJP4

Pathways: M Phase