LC3B antibody

Catalog No. ABIN969267

Cited in 2+ publications. The Mouse Monoclonal anti-LC3B antibody (Clone 5H12) (ABIN969267) specifically detects LC3B in ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for LC3B antibody (ABIN969267)

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LC3B antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 5H12

Product Details anti-LC3B Antibody

Purpose: MAP1LC3B Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human MAP1LC3B expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-LC3B antibody (ABIN969267)

Othman, Kaur, Mutee, Muhammad, Tan: "Immunohistochemical expression of MAP1LC3A and MAP1LC3B protein in breast carcinoma tissues." in: Journal of clinical laboratory analysis, Vol. 23, Issue 4, pp. 249-58, (2009) (PubMed).

Liu, Wang, Pan, Meng, Zhan, Zheng: "[Expression of autophagy-related genes Beclin1 and MAPLC3 in non-small cell lung cancer]." in: Ai zheng = Aizheng = Chinese journal of cancer, Vol. 27, Issue 1, pp. 25-9, (2008) (PubMed).

Target Details for LC3B

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Alternative Name: MAP1LC3B

Background: The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.

Molecular Weight: 14.6 kDa

Gene ID: 81631

UniProt: Q9GZQ8

Pathways: Autophagy