MAP3K2 antibody
(2 references)Quick Overview for MAP3K2 antibody (ABIN969272)
Target
See all MAP3K2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- MAP3K2 Antibody
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Purification
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human MAP3K2 expressed in E. Coli.
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Isotype
- IgG1
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) antibody
KD Validated MAP3K2 Reactivity: Human WB, ICC, FACS Host: Rabbit Monoclonal 24GB260 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 14-43), (N-Term) antibodyMAP3K2 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB34479 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 111-200) antibodyMAP3K2 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 357-619) antibodyMAP3K2 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (C-Term) antibodyMAP3K2 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 146-195) antibodyMAP3K2 Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Monkey, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (N-Term) antibodyMAP3K2 Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig, Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
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Application Notes
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13533-41, (2009) (PubMed).
: "Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 17, pp. 5541-51, (2009) (PubMed).
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: "MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13533-41, (2009) (PubMed).
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- MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
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Alternative Name
- MAP3K2
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Background
- The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.
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Molecular Weight
- 70 kDa
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UniProt
- Q9Y2U5
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Pathways
- MAPK Signaling
Target
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