MATN1 antibody

Catalog No. ABIN969278

There is 1 publication for this product available. The Mouse Monoclonal anti-MATN1 antibody is suitable to detect MATN1 in samples from Human. It has been validated for ELISA and ICC.

Quick Overview for MATN1 antibody (ABIN969278)

Target: MATN1 (Matrilin 1, Cartilage Matrix Protein (MATN1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MATN1 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC)

Clone: 5A8

Product Details anti-MATN1 Antibody

Purpose: MATN1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human MATN1 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-MATN1 antibody (ABIN969278)

Chamberlin, Ubagai, Mudd, Thomas, Pao, Nguyen, Levy, Greene, Freehauf, Chou: "Methionine adenosyltransferase I/III deficiency: novel mutations and clinical variations." in: American journal of human genetics, Vol. 66, Issue 2, pp. 347-55, (2000) (PubMed).

Target Details for MATN1

Target: MATN1 (Matrilin 1, Cartilage Matrix Protein (MATN1))

Alternative Name: MATN1

Background: This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.

Molecular Weight: 54 kDa

Gene ID: 4146

UniProt: P21941