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MCM2 antibody

MCM2 Reactivity: Human WB, IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 1-00E-07 unconjugated
Catalog No. ABIN969281
  • Target See all MCM2 Antibodies
    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
    Reactivity
    • 119
    • 70
    • 23
    • 10
    • 10
    • 9
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 124
    • 11
    • 2
    • 1
    Mouse
    Clonality
    • 125
    • 13
    Monoclonal
    Conjugate
    • 70
    • 9
    • 8
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MCM2 antibody is un-conjugated
    Application
    • 82
    • 49
    • 48
    • 28
    • 26
    • 25
    • 20
    • 19
    • 11
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human MCM2 expressed in E. coli.
    Clone
    1-00E-07
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Chuang, Teixeira, Wohlschlegel, Henze, Yates, Méndez, Reed: "Phosphorylation of Mcm2 by Cdc7 promotes pre-replication complex assembly during cell-cycle re-entry." in: Molecular cell, Vol. 35, Issue 2, pp. 206-16, (2009) (PubMed).

    Liaw, Boyd: "MCM 2 Expression in Basal Cell Carcinomas and Trichoepitheliomas." in: Journal of cutaneous pathology, Vol. 36, Issue 10, pp. 1121-2, (2009) (PubMed).

  • Target
    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
    Alternative Name
    MCM2 (MCM2 Products)
    Synonyms
    CG7538 antibody, DmMCM2 antibody, DmMcm2 antibody, DmeMCM2 antibody, Dmel\\CG7538 antibody, MCM2 antibody, MCM2-7 antibody, MCM2_DROME antibody, McM2 antibody, PCR3 antibody, dMCM2 antibody, l(3)rL074 antibody, XMcm2 antibody, bm28 antibody, ccnl1 antibody, cdc19 antibody, cdcl1 antibody, mitotin antibody, cb737 antibody, chunp6905 antibody, BM28 antibody, CCNL1 antibody, CDCL1 antibody, D3S3194 antibody, MITOTIN antibody, MCM7 antibody, AA959861 antibody, AW476101 antibody, Mcmd2 antibody, mKIAA0030 antibody, Minichromosome maintenance 2 antibody, minichromosome maintenance complex component 2 antibody, minichromosome maintenance complex component 2 L homeolog antibody, Mcm2 antibody, mcm2 antibody, MCM2 antibody, mcm2.L antibody
    Background

    Description: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.

    Aliases: BM28, CCNL1, CDCL1, cdc19, D3S3194, MITOTIN, KIAA0030, MGC10606

    Molecular Weight
    125 kDa
    Gene ID
    4171
    HGNC
    4171
    Pathways
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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