MSI1 antibody

Catalog No. ABIN969294

This anti-MSI1 antibody is a Mouse Monoclonal antibody detecting MSI1 in WB, ELISA and FACS. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for MSI1 antibody (ABIN969294)

Target: MSI1 (Musashi Homolog 1 (Drosophila) (MSI1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MSI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 2A12

Product Details anti-MSI1 Antibody

Purpose: MSI1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human MSI1 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-MSI1 antibody (ABIN969294)

Sureban, May, George, Dieckgraefe, McLeod, Ramalingam, Bishnupuri, Natarajan, Anant, Houchen: "Knockdown of RNA binding protein musashi-1 leads to tumor regression in vivo." in: Gastroenterology, Vol. 134, Issue 5, pp. 1448-58, (2008) (PubMed).

Target Details for MSI1

Target: MSI1 (Musashi Homolog 1 (Drosophila) (MSI1))

Alternative Name: MSI1

Background: This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas.Musashi-1 is frequently used as a marker for proliferating neural precursor cells, it is also expressed in epithelial stem cells including intestinal and mammary gland stem cells.Tissue specificity: Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.

Molecular Weight: 39 kDa

UniProt: O43347

Pathways: Stem Cell Maintenance