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MTHFR antibody

MTHFR Reactivity: Human, Rat WB, ELISA, IHC Host: Mouse Monoclonal 5D3 unconjugated
Catalog No. ABIN969297
  • Target See all MTHFR Antibodies
    MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))
    Reactivity
    • 50
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 46
    • 3
    • 2
    Mouse
    Clonality
    • 50
    • 1
    Monoclonal
    Conjugate
    • 21
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MTHFR antibody is un-conjugated
    Application
    • 38
    • 17
    • 13
    • 13
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human MTHFR expressed in E. coli.
    Clone
    5D3
    Isotype
    IgG1
    Top Product
    Discover our top product MTHFR Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Sarecka-Hujar, Zak, Krauze: "Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease." in: Kardiologia polska, Vol. 66, Issue 12, pp. 1269-77, (2009) (PubMed).

    Oliveira, Bianco, Bianco, Verreschi, Guedes, Galera, Galera, Barbosa, Lipay: "Prevalence of the polymorphism MTHFR A1298C and not MTHFR C677T is related to chromosomal aneuploidy in Brazilian Turner Syndrome patients." in: Arquivos brasileiros de endocrinologia e metabologia, Vol. 52, Issue 8, pp. 1374-81, (2009) (PubMed).

  • Target
    MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))
    Alternative Name
    MTHFR (MTHFR Products)
    Synonyms
    DDBDRAFT_0204686 antibody, DDBDRAFT_0230137 antibody, DDB_0204686 antibody, DDB_0230137 antibody, AI323986 antibody, methylenetetrahydrofolate reductase (NAD(P)H) L homeolog antibody, methylenetetrahydrofolate reductase antibody, methylenetetrahydrofolate reductase (NAD(P)H) antibody, 5,10-methylenetetrahydrofolate reductase antibody, mthfr.L antibody, MTHFR antibody, mthfr antibody, metF antibody, DDB_G0279137 antibody, Mthfr antibody
    Background

    Description: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

    Aliases: MTHFR

    Molecular Weight
    75 kDa
    Gene ID
    4524
    HGNC
    4524
    Pathways
    Methionine Biosynthetic Process
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