OTX2 antibody

Catalog No. ABIN969332

The Mouse Monoclonal anti-OTX2 antibody has been validated for WB, ELISA, IHC, FACS and ICC. It is suitable to detect OTX2 in samples from Human. There is 1 publication available.

Quick Overview for OTX2 antibody (ABIN969332)

Target: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This OTX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 1H12C4B5

Product Details anti-OTX2 Antibody

Purpose: OTX2 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human OTX2 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-OTX2 antibody (ABIN969332)

Wyatt, Bakrania, Bunyan, Osborne, Crolla, Salt, Ayuso, Newbury-Ecob, Abou-Rayyah, Collin, Robinson, Ragge: "Novel heterozygous OTX2 mutations and whole gene deletions in anophthalmia, microphthalmia and coloboma." in: Human mutation, Vol. 29, Issue 11, pp. E278-83, (2008) (PubMed).

Target Details for OTX2

Target: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Alternative Name: OTX2

Background: This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development.Tissue specificity: Expressed in brain.

Molecular Weight: 32 kDa

UniProt: P32243

Pathways: Dopaminergic Neurogenesis