PAR1 antibody

Catalog No. ABIN969339

Cited in 2+ publications. The Mouse Monoclonal anti-PAR1 antibody (Clone 6A7H10) (ABIN969339) specifically detects PAR1 in ELISA. The antibody is reactive with Human samples.

Quick Overview for PAR1 antibody (ABIN969339)

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAR1 antibody is un-conjugated

Application: ELISA

Clone: 6A7H10

Product Details anti-PAR1 Antibody

Purpose: PAR1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of PAR1 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-PAR1 antibody (ABIN969339)

Tantivejkul, Loberg, Mawocha, Day, John, Pienta, Rubin, Pienta: "PAR1-mediated NFkappaB activation promotes survival of prostate cancer cells through a Bcl-xL-dependent mechanism." in: Journal of cellular biochemistry, Vol. 96, Issue 3, pp. 641-52, (2005) (PubMed).

Nakayama, Kawato, Watanabe, Ohtsuka, Yoshida, Yokomizo, Sakamoto, Kuru, Ohta, Hoshino, Yoshida, Ishida, Cho, Palme, Zhang, Lee, Watkins: "MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 3: Optimization of potency in the pyridopyrimidine series through the application of a pharmacophore model." in: Bioorganic & medicinal chemistry letters, Vol. 14, Issue 2, pp. 475-9, (2003) (PubMed).

Target Details for PAR1

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Alternative Name: PAR1

Background: PAR1: Prader-Willi/Angelman region-1 .

Gene ID: 145624

Pathways: Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus