Cardiac Troponin T2 antibody

Catalog No. ABIN969445

This Mouse Monoclonal antibody specifically detects Cardiac Troponin T2 in ELISA and FACS. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for Cardiac Troponin T2 antibody (ABIN969445)

Target: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cardiac Troponin T2 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 1G1

Product Details anti-Cardiac Troponin T2 Antibody

Purpose: troponin T2 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human troponin T2 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Cardiac Troponin T2 antibody (ABIN969445)

Luedde, Ehlermann, Weichenhan, Will, Zeller, Rupp, Müller, Steen, Ivandic, Ulmer, Kern, Katus, Frey: "Severe familial left ventricular non-compaction cardiomyopathy due to a novel troponin T (TNNT2) mutation." in: Cardiovascular research, Vol. 86, Issue 3, pp. 452-60, (2010) (PubMed).

Target Details for Cardiac Troponin T2

Target: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Alternative Name: troponin T2

Background: The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Molecular Weight: 36 kDa

Gene ID: 7139

UniProt: P45379