WNT10B antibody

Catalog No. ABIN969459

Cited in 1 publication. The Mouse Monoclonal anti-WNT10B antibody (Clone 5A7) (ABIN969459) specifically detects WNT10B in WB, IHC, ELISA and ICC. The antibody is reactive with Human samples.

Quick Overview for WNT10B antibody (ABIN969459)

Target: WNT10B (Wingless-Type MMTV Integration Site Family, Member 10B (WNT10B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This WNT10B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone: 5A7

Product Details anti-WNT10B Antibody

Purpose: WNT10B Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human WNT10B expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-WNT10B antibody (ABIN969459)

Saitoh, Kirikoshi, Mine, Katoh: "Proto-oncogene WNT10B is up-regulated by tumor necrosis factor alpha in human gastric cancer cell line MKN45." in: International journal of oncology, Vol. 19, Issue 6, pp. 1187-92, (2001) (PubMed).

Target Details for WNT10B

Target: WNT10B (Wingless-Type MMTV Integration Site Family, Member 10B (WNT10B))

Alternative Name: WNT10B

Background: WNT10B: wingless-type MMTV integration site family, member 10B. The WNT family consists of structurally related secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT10B is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is ikely a molecular switch that governs adipogenesis. This protein is 96 % identical to the mouse Wnt10B protein at the amino acid level. The WNT10B gene is clustered with another family member, WNT1, in the chromosome 12q13 region.

Molecular Weight: 43 kDa

UniProt: O00744

Pathways: WNT Signaling, Skeletal Muscle Fiber Development