ZBTB16 antibody

Catalog No. ABIN969465

This anti-ZBTB16 antibody is a Mouse Monoclonal antibody detecting ZBTB16 in WB, ELISA and ICC. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for ZBTB16 antibody (ABIN969465)

Target: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZBTB16 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 5B3

Product Details anti-ZBTB16 Antibody

Purpose: ZBTB16 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human ZBTB16 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-ZBTB16 antibody (ABIN969465)

Felicetti, Errico, Bottero, Segnalini, Stoppacciaro, Biffoni, Felli, Mattia, Petrini, Colombo, Peschle, Carè: "The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms." in: Cancer research, Vol. 68, Issue 8, pp. 2745-54, (2008) (PubMed).

Target Details for ZBTB16

Target: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Alternative Name: ZBTB16

Background: This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. Tissue specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.

Molecular Weight: 74 kDa

UniProt: Q05516

Pathways: Positive Regulation of fat Cell Differentiation