DLL4 antibody

Catalog No. ABIN969514

This Mouse Monoclonal antibody specifically detects DLL4 in ELISA and FACS. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for DLL4 antibody (ABIN969514)

Target: DLL4 (delta-Like 4 (DLL4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DLL4 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 4A11G2

Product Details anti-DLL4 Antibody

Purpose: DLL4 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human DLL4 expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-DLL4 antibody (ABIN969514)

Al Haj Zen, Oikawa, Bazan-Peregrino, Meloni, Emanueli, Madeddu: "Inhibition of delta-like-4-mediated signaling impairs reparative angiogenesis after ischemia." in: Circulation research, Vol. 107, Issue 2, pp. 283-93, (2010) (PubMed).

Sheldon, Heikamp, Turley, Dragovic, Thomas, Oon, Leek, Edelmann, Kessler, Sainson, Sargent, Li, Harris: "New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes." in: Blood, Vol. 116, Issue 13, pp. 2385-94, (2010) (PubMed).

Target Details for DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Alternative Name: DLL4

Background: This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.

Molecular Weight: 74.6 kDa

Gene ID: 54567

UniProt: Q9NR61

Pathways: Notch Signaling