DLL4 antibody (AA 313-439)

Catalog No. ABIN969515

The Mouse Monoclonal anti-DLL4 antibody has been validated for ELISA and IHC. It is suitable to detect DLL4 in samples from Human. There are 2+ publications available.

Quick Overview for DLL4 antibody (AA 313-439) (ABIN969515)

Target: DLL4 (delta-Like 4 (DLL4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DLL4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Clone: 4A11F8

Product Details anti-DLL4 Antibody

Binding Specificity: AA 313-439

Purpose: DLL4 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human DLL4 (AA: 313-439) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-DLL4 antibody (ABIN969515)

Jubb, Soilleux, Turley, Steers, Parker, Low, Blades, Li, Allen, Leek, Noguera-Troise, Gatter, Thurston, Harris: "Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer." in: The American journal of pathology, Vol. 176, Issue 4, pp. 2019-28, (2010) (PubMed).

Sheldon, Heikamp, Turley, Dragovic, Thomas, Oon, Leek, Edelmann, Kessler, Sainson, Sargent, Li, Harris: "New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes." in: Blood, Vol. 116, Issue 13, pp. 2385-94, (2010) (PubMed).

Target Details for DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Alternative Name: DLL4

Background: This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.

Molecular Weight: 74.6 kDa

Gene ID: 54567

UniProt: Q9NR61

Pathways: Notch Signaling