Lp(a) antibody (AA 4330-4521)
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- Target
- Lp(a) (Lipoprotein (Lp(a)))
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Binding Specificity
- AA 4330-4521
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Lp(a) antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human LPA (AA: 4330-4521) expressed in E. coli. ,
- Clone
- 4H1
- Isotype
- IgG1
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Lipoprotein(a) levels and long-term cardiovascular risk in the contemporary era of statin therapy." in: Journal of lipid research, Vol. 51, Issue 10, pp. 3055-61, (2010) (PubMed).
: "Serum lipoprotein (a) levels in patients with first unprovoked venous thromboembolism is not associated with subsequent risk of recurrent VTE." in: Thrombosis research, Vol. 126, Issue 3, pp. 222-6, (2010) (PubMed).
: "
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Lipoprotein(a) levels and long-term cardiovascular risk in the contemporary era of statin therapy." in: Journal of lipid research, Vol. 51, Issue 10, pp. 3055-61, (2010) (PubMed).
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- Target
- Lp(a) (Lipoprotein (Lp(a)))
- Alternative Name
- LPA
- Background
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Description: The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence.
Aliases: LP, AK38, APOA
- Molecular Weight
- 501 kDa
- Gene ID
- 4018
- HGNC
- 4018
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