SOX9 antibody

Catalog No. ABIN969568

This Mouse Monoclonal antibody specifically detects SOX9 in WB, ELISA and ICC. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for SOX9 antibody (ABIN969568)

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SOX9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 1B11

Product Details anti-SOX9 Antibody

Purpose: SOX9 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human SOX9 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-SOX9 antibody (ABIN969568)

Dupasquier, Abdel-Samad, Glazer, Bastide, Jay, Joubert, Cavaillès, Blache, Quittau-Prévostel: "A new mechanism of SOX9 action to regulate PKCalpha expression in the intestine epithelium." in: Journal of cell science, Vol. 122, Issue Pt 13, pp. 2191-6, (2009) (PubMed).

Gordon, Tan, Benko, Fitzpatrick, Lyonnet, Farlie: "Long-range regulation at the SOX9 locus in development and disease." in: Journal of medical genetics, Vol. 46, Issue 10, pp. 649-56, (2009) (PubMed).

Target Details for SOX9

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Alternative Name: SOX9

Background: The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

Molecular Weight: 56 kDa

Gene ID: 6662

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development