Aubergine antibody (Internal Region)
aub
Reactivity: Drosophila melanogaster
ELISA, WB
Host: Rabbit
Polyclonal
unconjugated
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- Target
- Aubergine (aub)
- Binding Specificity
- Internal Region
- Reactivity
- Drosophila melanogaster
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- ELISA, Western Blotting (WB)
- Immunogen
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an of Drosophila melanogaster Aubergine/Sting protein.
- Isotype
- IgG
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- Application Notes
- Aubergine affinity-purified antibody has been tested for use in ELISA. Specific conditions for reactivity should be optimized by the end user. By western blot a band approximately 98 kDa in size corresponding to Aubergine protein is expected in the appropriate cell lysate or extract.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Preservative
- Sodium azide
- Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Storage
- -20 °C
-
- Target
- Aubergine (aub)
- Alternative Name
- Aubergine/Sting
- Synonyms
- AUB antibody, Aub antibody, CG6137 antibody, Dmel\\CG6137 antibody, ms(2)32D antibody, sti antibody, sting antibody, GB10293 antibody, Piwi antibody, SIWI antibody, siwi1 antibody, aubergine antibody, aubergine protein antibody, aub antibody, Aubergine antibody
- Target Type
- Species
- Background
-
Aubergine (Sting) is a Drosophila protein involved in germ-line development and RNA interference. Drosophila melanogaster has a robust and efficient innate immune system, which reacts to infections ranging from bacteria to fungi and, as discovered recently, viruses as well. The known Drosophila immune responses rely on humoral and cellular activities, similar to those found in the innate immune system of other animals. Recently, RNAi or 'RNA silencing' has arisen as a possible means by which Drosophila can react to specific pathogens, transposons and retroviral elements, in a fashion similar to that of a traditional mammalian adaptive immune system instead of in a more generalized and genome encoded innate immune-based response. RNAi is a highly conserved regulation and defense mechanism, which suppresses gene expression via targeted RNA degradation directed by either exogenous dsRNA (cleaved into siRNAs) or endogenous miRNAs. In plants, RNAi has been found to act as an antiviral immune response system. In Drosophila multiple core RNAi pathway genes have been reported, including piwi, vasa intronic gene (vig), aubergine (aub), armitage (armi), Rm62, r2d2 and Argonaute2 (AGO2).
Synonyms: AUBERGINE Aubergine, isoform A Sting - Gene ID
- 34524, 17136494
- UniProt
- O76922
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