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BRSK1 ELISA Kits

(BR Serine/threonine Kinase 1 (BRSK1))
Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Ser-573'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity in polarized neurons. Also acts as a positive regulator of centrosome duplication by mediating phosphorylation of gamma-tubulin (TUBG1 and TUBG2) at 'Ser-131', leading to translocation of gamma-tubulin and its associated proteins to the centrosome. Involved in the UV- induced DNA damage checkpoint response, probably by inhibiting CDK1 activity through phosphorylation and activation of WEE1, and inhibition of CDC25B and CDC25C (By similarity). In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possibly by phosphorylating RIMS1.
BRSK1 ELISA Kit (ABIN5648007)

BRSK1 Reactivity: Human, Mouse Colorimetric Cell ELISA Cell Culture Cells

BRSK1 ELISA Kit (ABIN1157191)

BRSK1 Reactivity: Rat Colorimetric

BRSK1 ELISA Kits by Reactivity

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Popular BRSK1 ELISA Kits

Aliases for BRSK1 ELISA Kits

BR serine/threonine kinase 1 (BRSK1) ELISA Kits
BR serine/threonine kinase 1 (Brsk1) ELISA Kits
BRSK1 ELISA Kits
Gm1100 ELISA Kits
hSAD1 ELISA Kits
RGD1563268 ELISA Kits
SAD-B ELISA Kits
Sad-b ELISA Kits
SADB ELISA Kits
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