C6 Products
(Complement Component 6 (C6))
Categories
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012].
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Featured C6 Categories
C6 Antibodies
High quality antibodies with extensive validation data.
C6 ELISA Kits
Reliable ELISA kits for a wide range of species.
C6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended C6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7435277
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IF, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN390924
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS, IF
Validations
- (7)
Cat. No.
ABIN3029693
Quantity
0.4 mL
Datasheet
Datasheet
Recommended C6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966018
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955020
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN4968268
Quantity
96 tests
Datasheet
Datasheet
Recommended C6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1776082
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3091807
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7198986
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our C6 products
: "Interaction between Multimeric von Willebrand Factor and Complement: A Fresh Look to the Pathophysiology of Microvascular Thrombosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 3, pp. 1021-1040, (2017) (PubMed).: "Sublytic C5b-9 induces IL-6 and TGF-?1 production by glomerular mesangial cells in rat Thy-1 nephritis through p300-mediated C/EBP? acetylation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 3, pp. 1511-25, (2014) (PubMed).
: "Molecular mechanisms of complement component C6 deficiency; a hypervariable exon 6 region responsible for three of six reported defects." in: Clinical and experimental immunology, Vol. 119, Issue 2, pp. 255-8, (2000) (PubMed).
: "High prevalence of complement component C6 deficiency among African-Americans in the south-eastern USA." in: Clinical and experimental immunology, Vol. 119, Issue 2, pp. 305-10, (2000) (PubMed).
: "The terminal sequence of complement plays an essential role in antibody-mediated renal cell apoptosis." in: Journal of the American Society of Nephrology : JASN, Vol. 10, Issue 6, pp. 1242-52, (1999) (PubMed).
: "Depletion of C6 prevents development of proteinuria in experimental membranous nephropathy in rats." in: The American journal of pathology, Vol. 135, Issue 1, pp. 185-94, (1989) (PubMed).
: "Increased urinary excretion of C5b-9 distinguishes passive Heymann nephritis in the rat." in: Kidney international, Vol. 35, Issue 1, pp. 60-8, (1989) (PubMed).
Synonyms and alternative names related to C6
complement component 6 (c6), complement C6 (C6), complement component 6, gene 1 L homeolog (c6.1.L), complement component 6, gene 2 (c6.2), complement component 6 (C6), AW111623, c6, C6, MGC82168, MGC89471, zgc:64073Protein level used designations for C6
- complement component C6
- sixth complement component
- complement component 6
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