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CCL21 Products

(Chemokine (C-C Motif) Ligand 21 (CCL21))

Categories

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Jul 2008].

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Featured CCL21 Categories

CCL21 Antibodies

High quality antibodies with extensive validation data.

CCL21 ELISA Kits

Reliable ELISA kits for a wide range of species.

CCL21 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CCL21 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7433810
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7438628
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7438607
Quantity 100 μL
Datasheet Datasheet

Recommended CCL21 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965675
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6963193
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954605
Quantity 96 tests
Datasheet Datasheet

Recommended CCL21 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5509305
Quantity 20 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122282
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348392
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our CCL21 products

Ji, Ye, Nie, Peng, Fu, Wang, Tong: "Dysregulation of miR-142 results in anxiety-like behaviors following single prolonged stress." in: Behavioural brain research, Vol. 365, pp. 157-163, (2020) (PubMed).

Wang, Zhao: "Sigma-1 receptor activation ameliorates LPS-induced NO production and ROS formation through the Nrf2/HO-1 signaling pathway in cultured astrocytes." in: Neuroscience letters, Vol. 711, pp. 134387, (2020) (PubMed).

Nie, Ji, Fu, Peng, Wang, Tong: "miR-132 Regulates PTSD-like Behaviors in Rats Following Single-Prolonged Stress Through Fragile X-Related Protein 1." in: Cellular and molecular neurobiology, (2020) (PubMed).

Gao, Camous, Lu, Lim, Larbi, Ng: "Novel inflammatory markers associated with cognitive performance: Singapore Longitudinal Ageing Studies." in: Neurobiology of aging, Vol. 39, pp. 140-6, (2016) (PubMed).

Borrelli, Abrão, Taube, Darb-Esfahani, Köhler, Kaufmann, Chiantera, Mechsner: "Immunohistochemical Investigation of Metastasis-Related Chemokines in Deep-Infiltrating Endometriosis and Compromised Pelvic Sentinel Lymph Nodes." in: Reproductive sciences (Thousand Oaks, Calif.), (2015) (PubMed).

Mitchell, Batich, Gunn, Huang, Sanchez-Perez, Nair, Congdon, Reap, Archer, Desjardins, Friedman, Friedman, Herndon, Coan, McLendon, Reardon, Vredenburgh, Bigner, Sampson: "Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients." in: Nature, Vol. 519, Issue 7543, pp. 366-9, (2015) (PubMed).

Chen, Luo, Wen, Li, Li, Wang, Du, Zhang, Tang, Yang, Hu, Zhao, Wei: "Low-dose paclitaxel improves the therapeutic efficacy of recombinant adenovirus encoding CCL21 chemokine against murine cancer." in: Cancer science, Vol. 105, Issue 11, pp. 1393-401, (2015) (PubMed).

Bicer, Altuntas, Izgi, Ozer, Kavran, Tuohy, Daneshgari: "Chronic pelvic allodynia is mediated by CCL2 through mast cells in an experimental autoimmune cystitis model." in: American journal of physiology. Renal physiology, Vol. 308, Issue 2, pp. F103-13, (2015) (PubMed).

Nonaka, Bao, Matsumura, Götze, Kandasamy, Kononov, Broide, Nakayama, Seeberger, Fukuda: "Synthetic di-sulfated iduronic acid attenuates asthmatic response by blocking T-cell recruitment to inflammatory sites." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 22, pp. 8173-8, (2014) (PubMed).

Andersson, Nilsson, Fagerberg, Hallström, Sundström, Danielsson, Edlund, Uhlen, Asplund: "The transcriptomic and proteomic landscapes of bone marrow and secondary lymphoid tissues." in: PLoS ONE, Vol. 9, Issue 12, pp. e115911, (2014) (PubMed).

Synonyms and alternative names related to CCL21

C-C motif chemokine ligand 21 (CCL21), C-C motif chemokine 21 (ccl21), C-C motif chemokine ligand 21 (Ccl21), 6Ckine, ccl21, Ccl21b, CKb9, ECL, SCYA21, SLC, TCA4

Protein level used designations for CCL21

  • C-C motif chemokine 21
  • Efficient Chemoattractant for Lymphocytes
  • beta chemokine exodus-2
  • secondary lymphoid tissue chemokine
  • small inducible cytokine subfamily A (Cys-Cys), member 21
  • CC chemokine ligand 21
  • putative CCL21 chemokine
  • chemokine CCL21/6CKINE
  • small-inducible cytokine A21
  • small inducible cytokine A21
  • CCL21
  • chemokine (C-C motif) ligand 21
  • chemokine (C-C motif) ligand 21b (serine)
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