CFLA antibody (Center)
VVL
Reactivity: Human
FACS, IHC, WB
Host: Rabbit
Polyclonal
unconjugated
-
- Target
- CFLA (VVL) (POU Domain Protein CF1A (VVL))
- Binding Specificity
- AA 145-174, Center
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
- Purpose
- Rabbit Anti-Human CFLAR (Center) Antibody
- Immunogen
- This CFLAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the Central region of human CFLAR.
- Isotype
- Ig Fraction
-
- Application Notes
-
Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100, FC: 1:10-50Western blot analysis of CFLAR Antibody (Center) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 2.000 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
-
- Target
- CFLA (VVL) (POU Domain Protein CF1A (VVL))
- Alternative Name
- CFLA
- Background
-
Target Description: Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. It lacks enzymatic (caspase) activity.
Gene Symbol: CFLAR
- Molecular Weight
- 55344 Da
- Gene ID
- 8837
- UniProt
- O15519
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