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Cofilin Products

(Cofilin 1 (CFL1))
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004].

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Featured Cofilin Categories

Cofilin Antibodies

High quality antibodies with extensive validation data.

Cofilin ELISA Kits

Reliable ELISA kits for a wide range of species.

Cofilin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Cofilin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (4)
  • (8)
Cat. No. ABIN514354
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC, IHC (fro)
Validations
  • (2)
  • (7)
Cat. No. ABIN2855302
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (8)
Cat. No. ABIN7433783
Quantity 100 μL
Datasheet Datasheet

Recommended Cofilin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6954890
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965917
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965916
Quantity 96 tests
Datasheet Datasheet

Recommended Cofilin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122422
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349217
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN666701
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Cofilin products

Lee, Du, Hwa, Kim: "Parkin Coordinates Platelet Stress Response in Diabetes Mellitus: A Big Role in a Small Cell." in: International journal of molecular sciences, Vol. 21, Issue 16, (2020) (PubMed).

Chen, Lin, Tsai, He, Luo, Chiu, Herschman, Li: "Exosomal 2',3'-CNP from mesenchymal stem cells promotes hippocampus CA1 neurogenesis/neuritogenesis and contributes to rescue of cognition/learning deficiencies of damaged brain." in: Stem cells translational medicine, Vol. 9, Issue 4, pp. 499-517, (2020) (PubMed).

Yee, Nichols, Polley, Saifeddine, Pal, Lee, Wilson, Daines, Hollenberg, Boitano, DeFea: "Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 315, Issue 6, pp. L1042-L1057, (2019) (PubMed).

Rangel, Antonangelo, Acencio, Faria, de Sá, Leão, Farhat, Fabro, Longatto Filho, Reis, Takagaki, Capelozzi: "Detection of sputum cofilin-1 as indicator of malignancy." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, Vol. 51, Issue 8, pp. e7138, (2018) (PubMed).

Niu, Pi, Baral, Xia, He, Li, Jin, Li, Wang, Mao, Hu: "P2Y12 Promotes Migration of Vascular Smooth Muscle Cells Through Cofilin Dephosphorylation During Atherogenesis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 37, Issue 3, pp. 515-524, (2017) (PubMed).

Ortea, Roschitzki, López-Rodríguez, Tomero, Ovalles, López-Longo, de la Torre, González-Alvaro, Gómez-Reino, González: "Independent Candidate Serum Protein Biomarkers of Response to Adalimumab and to Infliximab in Rheumatoid Arthritis: An Exploratory Study." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153140, (2016) (PubMed).

Ghoshal, Singla, Lin, Feck, Cantu-Medellin, Kelley, Haigh, Fulton, Csányi: "Nox2-Mediated PI3K and Cofilin Activation Confers Alternate Redox Control of Macrophage Pinocytosis." in: Antioxidants & redox signaling, (2016) (PubMed).

Hu, Guo, Feng, Zhang, Zhou, Ma, Shen, Tong, Yan, Zhu, Bian, Lai, Deng, Ding: "MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis." in: Oncotarget, Vol. 6, Issue 26, pp. 22410-23, (2016) (PubMed).

Grzanka, Kowalczyk, Izdebska, Klimaszewska-Wisniewska, Gagat: "The interactions between SATB1 and F-actin are important for mechanisms of active cell death." in: Folia histochemica et cytobiologica, Vol. 53, Issue 2, pp. 152-61, (2015) (PubMed).

Tang, Baykal, Gao, Quezada, Zhang, Bereczki, Serhatli, Baykal, Acioglu, Wang, Ioja, Ji, Zhang, Guan, Winblad, Pei: "mTor is a signaling hub in cell survival: a mass-spectrometry-based proteomics investigation." in: Journal of proteome research, Vol. 13, Issue 5, pp. 2433-44, (2014) (PubMed).

Synonyms and alternative names related to Cofilin

cofilin 1 (non-muscle) L homeolog (cfl1.L), cofilin 1 (non-muscle) (cfl1), cofilin 1 (non-muscle), like (cfl1l), cofilin 1 (CFL1), twinstar (tsr), cofilin (COF1), cofilin (TSTA_042790), cofilin 1 (Cfl1), cofilin 1, non-muscle (Cfl1), Contrafreeloading (CFL), 12/8, AA959946, ADF, Adf, ADF/cofilin, Cadf, cb86, cfl, CFL, cfl1, CFL1, CG4254, Cof, cofilin, cofilin/actin depolymerizing factor homolog, cofilin/ADF, D-cof, D61, Dmel\\CG4254, l(2)03101, l(2)k03101, l(2)k05633, l(2)k13409, ntf, sb:cb86, T8, Tsr, wu:fb18a04, wu:fk77b03, xac1, xac2, zgc:56501

Protein level used designations for Cofilin

  • ADF/cofilin-1
  • cofilin-1-A
  • ADF/cofilin
  • cofilin-1
  • non-muscle cofilin 1
  • cofilin 1 (non-muscle)
  • ADFcofilin
  • CG4254-PA
  • Cofilin/actin depolymerizing factor-like
  • DCofilin
  • actin-depolymerizing factor
  • cofilin
  • no terminal filament
  • tsr-PA
  • twin star
  • Cof1p
  • 18 kDa phosphoprotein
  • cofilin, non-muscle isoform
  • p18
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