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Complement C2 Products

(Complement C2)

Categories

Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.[provided by RefSeq, Mar 2009].

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Featured Complement C2 Categories

Complement C2 Antibodies

High quality antibodies with extensive validation data.

Complement C2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Complement C2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Complement C2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7432784
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7442954
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IF
Validations
  • (2)
Cat. No. ABIN2856098
Quantity 100 μL
Datasheet Datasheet

Recommended Complement C2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954987
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965991
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962755
Quantity 96 tests
Datasheet Datasheet

Recommended Complement C2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274034
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274035
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1347399
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our Complement C2 products

Kostrzewa-Nowak, Kubaszewska, Nowakowska, Nowak: "Effect of Aerobic and Anaerobic Exercise on the Complement System of Proteins in Healthy Young Males." in: Journal of clinical medicine, Vol. 9, Issue 8, (2020) (PubMed).

Bhattad, Rawat, Gupta, Suri, Garg, de Boer, Kuijpers, Singh: "Early Complement Component Deficiency in a Single-Centre Cohort of Pediatric Onset Lupus." in: Journal of clinical immunology, Vol. 35, Issue 8, pp. 777-85, (2015) (PubMed).

Synonyms and alternative names related to Complement C2

complement C2 (C2), complement component 2 (within H-2S) (C2), CO2

Protein level used designations for Complement C2

  • complement C2
  • C3/C5 convertase
  • complement component C2
  • MHC complement component C2
  • classical-complement pathway C3/C5 convertase
  • complement factor C2
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