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COMT Antibodies

(Catechol-O-Methyltransferase (COMT))
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008].
COMT antibody  (Internal Region) COMT antibody  (Internal Region) COMT antibody (Internal Region) (ABIN185682)

Verified COMT Reactivity: Human ELISA, EIA, IHC, WB Host: Goat Polyclonal unconjugated

COMT antibody  (AA 52-271) COMT antibody  (AA 52-271) COMT antibody (AA 52-271) (ABIN3043815)

COMT Reactivity: Human, Mouse, Rat ICC, IHC (p), WB Host: Rabbit Polyclonal unconjugated

COMT antibody  (Center) COMT antibody  (Center) COMT antibody (Center) (ABIN2854980)

COMT Reactivity: Human, Mouse IHC (p), ELISA, WB Host: Rabbit Polyclonal unconjugated

COMT Antibodies by Grade

Find COMT Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

COMT Antibodies by Reactivity

Find COMT Antibodies for a variety of species such as anti-Human COMT, anti-Mouse COMT, anti-Rat COMT. The species listed below are among those available. Click on a link to go to the corresponding products.

COMT Antibodies by Application

Find COMT Antibodies validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

COMT Antibodies by Host

Find COMT Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

COMT Antibodies by Binding Specificity

Find COMT Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

COMT Antibodies by Clonality

Find available monoclonal or polyclonal COMT Antibodies. Click on a link to go to the corresponding products.

COMT Antibodies by Clone

Find COMT Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

COMT Antibodies by Conjugate

Find COMT Antibodies with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular COMT Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, EIA, IHC, WB
Validations
  • (6)
Cat. No. ABIN185682
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ICC, IHC (p), WB
Validations
  • (8)
Cat. No. ABIN3043815
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC (p), ELISA, WB
Validations
  • (1)
  • (4)
Cat. No. ABIN2854980
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (4)
Cat. No. ABIN560435
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF, IHC
Validations
  • (3)
Cat. No. ABIN7010982
Quantity 60 μL
Datasheet Datasheet
Reactivity Bat, Cow, Human, Monkey, Mouse, Pig, Rat
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN768668
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application IP, WB
Validations
  • (3)
Cat. No. ABIN1679321
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (3)
Cat. No. ABIN2781821
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IP, WB
Validations
  • (3)
Cat. No. ABIN514524
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN514522
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7127433
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, ICC, IF, IHC, WB
Validations
  • (1)
  • (1)
Cat. No. ABIN6258028
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
  • (1)
Cat. No. ABIN1882224
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN185328
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN1682443
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our COMT Antibodies

Bai, Tang, Zou, Meng, Tu, Xia, Cheng, Zhang, Yang, Mu, Wang, Qin, Lv, Cao, Qin, Jiang, Chen: "m6A Demethylase FTO Regulates Dopaminergic Neurotransmission Deficits Caused by Arsenite." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 165, Issue 2, pp. 431-446, (2018) (PubMed).

Ikeda, Iijima, Shinoda, Iwamoto, Takeda: "Inhibitory Effect of Bovine Lactoferrin on Catechol-O-Methyltransferase." in: Molecules (Basel, Switzerland), Vol. 22, Issue 8, (2018) (PubMed).

Yang, Yao, Zhou, Yin, Zhang, Harris: "Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury." in: American journal of physiology. Renal physiology, Vol. 302, Issue 6, pp. F742-9, (2012) (PubMed).

Hevir, Sinkovec, Rižner: "Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: lower levels of CYP1B1 and increased expression of S-COMT." in: Molecular and cellular endocrinology, Vol. 331, Issue 1, pp. 158-67, (2010) (PubMed).

Zeng, Ye, Lu, Chua, Tan, Zhong: "Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes." in: Organic letters, Vol. 12, Issue 10, pp. 2414-7, (2010) (PubMed).

Stroth, Reinhardt, Thöne, Hille, Schneider, Härtel, Weidemann, Bös, Spitzer: "Impact of aerobic exercise training on cognitive functions and affect associated to the COMT polymorphism in young adults." in: Neurobiology of learning and memory, Vol. 94, Issue 3, pp. 364-72, (2010) (PubMed).

Lim, Kim, Kim, Park, Han, Han, Lee, Yang, Ryu: "Genetic polymorphism of catechol-O-methyltransferase and cytochrome P450c17α in preeclampsia." in: Pharmacogenetics and genomics, Vol. 20, Issue 10, pp. 605-10, (2010) (PubMed).

Demetrovics, Varga, Szekely, Vereczkei, Csorba, Balazs, Hoffman, Sasvari-Szekely, Barta: "Association between Novelty Seeking of opiate-dependent patients and the catechol-O-methyltransferase Val(158)Met polymorphism." in: Comprehensive psychiatry, Vol. 51, Issue 5, pp. 510-5, (2010) (PubMed).

Bodenmann, Landolt: "Effects of modafinil on the sleep EEG depend on Val158Met genotype of COMT." in: Sleep, Vol. 33, Issue 8, pp. 1027-35, (2010) (PubMed).

Yao, Harris, Zhang: "Intrarenal dopamine attenuates deoxycorticosterone acetate/high salt-induced blood pressure elevation in part through activation of a medullary cyclooxygenase 2 pathway." in: Hypertension (Dallas, Tex. : 1979), Vol. 54, Issue 5, pp. 1077-83, (2009) (PubMed).

Aliases for COMT Antibodies

catechol-O-methyltransferase (COMT) Antibodies
catechol-O-methyltransferase (Comt) Antibodies
microRNA 4761 (MIR4761) Antibodies
catechol-O-methyltransferase (comt) Antibodies
catechol-O-methyltransferase (comt.2) Antibodies
catechol-O-methyltransferase S homeolog (comt.S) Antibodies
methyltransferase (Rv1703c) Antibodies
catechol-o-methyltransferase (Mb1729c) Antibodies
catechol-O-methyltransferase b (comtb) Antibodies
catechol O-methyltransferase (LOC100354142) Antibodies
COMT Antibodies
comt Antibodies
Comt1 Antibodies
D16Wsu103e Antibodies
D330014B15Rik Antibodies
mb-comt Antibodies
MGC154444 Antibodies
s-comt Antibodies
si:dkey-13a21.15 Antibodies
zgc:162236 Antibodies
zK13A21.15 Antibodies
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