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CSH1 Products

(Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))

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The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation\; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity. [provided by RefSeq, Jul 2008].

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Featured CSH1 Categories

CSH1 Antibodies

High quality antibodies with extensive validation data.

CSH1 ELISA Kits

Reliable ELISA kits for a wide range of species.

CSH1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

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Cat. No. ABIN7237186
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Latest Publications for our CSH1 products

Markl-Hahn, Neugebauer, Lenke, Ecker, Merz, McCook, Khoder, Brucker, Radermacher, Waller, Clapp, Bertsch, Triebel: "Human Placental Tissue Contains A Placental Lactogen-Derived Vasoinhibin." in: Journal of the Endocrine Society, Vol. 6, Issue 4, pp. bvac029, (2022) (PubMed).

Voorhees, Brooks: "Obligate ordered binding of human lactogenic cytokines." in: The Journal of biological chemistry, Vol. 285, Issue 26, pp. 20022-30, (2010) (PubMed).

Männik, Vaas, Rull, Teesalu, Rebane, Laan: "Differential expression profile of growth hormone/chorionic somatomammotropin genes in placenta of small- and large-for-gestational-age newborns." in: The Journal of clinical endocrinology and metabolism, Vol. 95, Issue 5, pp. 2433-42, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Varvarigou, Liatsis, Vassilakos, Decavalas, Beratis: "Effect of maternal smoking on cord blood estriol, placental lactogen, chorionic gonadotropin, FSH, LH, and cortisol." in: Journal of perinatal medicine, Vol. 37, Issue 4, pp. 364-9, (2009) (PubMed).

Chen, Kibriya, Jasmine, Santella, Senie, Ahsan: "Do placental genes affect maternal breast cancer? Association between offspring's CGB5 and CSH1 gene variants and maternal breast cancer risk." in: Cancer research, Vol. 68, Issue 23, pp. 9729-34, (2008) (PubMed).

Maidji, McDonagh, Genbacev, Tabata, Pereira: "Maternal antibodies enhance or prevent cytomegalovirus infection in the placenta by neonatal Fc receptor-mediated transcytosis." in: The American journal of pathology, Vol. 168, Issue 4, pp. 1210-26, (2006) (PubMed).

Goodrum, Jacobson: "Cephalic flexure formation in the chick embryo." in: The Journal of experimental zoology, Vol. 216, Issue 3, pp. 399-408, (1981) (PubMed).

Synonyms and alternative names related to CSH1

chorionic somatomammotropin hormone 1 (CSH1), chorionic somatomammotropin hormone 2 (CSH2), CS-1, CS-2, CSA, CSB, CSMT, hCS-A, hCS-B, PL

Protein level used designations for CSH1

  • choriomammotropin
  • chorionic somatomammotropin A
  • chorionic somatomammotropin hormone
  • placental lactogen
  • chorionic somatomammotropin B
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