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DHODH Products

(Dihydroorotate Dehydrogenase (DHODH))
The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008].

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Featured DHODH Categories

DHODH Antibodies

High quality antibodies with extensive validation data.

DHODH ELISA Kits

Reliable ELISA kits for a wide range of species.

DHODH Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DHODH Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7436645
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN560602
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN6259034
Quantity 100 μL
Datasheet Datasheet

Recommended DHODH ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955388
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955389
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1129714
Quantity 96 tests
Datasheet Datasheet

Recommended DHODH Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122667
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351544
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2719446
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our DHODH products

Sykes, Kfoury, Mercier, Wawer, Law, Haynes, Lewis, Schajnovitz, Jain, Lee, Meyer, Pierce, Tolliday, Waller, Ferrara, Eheim, Stoeckigt, Maxcy, Cobert, Bachand, Szekely, Mukherjee, Sklar, Kotz, Clish et al.: "Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia. ..." in: Cell, Vol. 167, Issue 1, pp. 171-186.e15, (2016) (PubMed).

Lucas-Hourani, Dauzonne, Jorda, Cousin, Lupan, Helynck, Caignard, Janvier, André-Leroux, Khiar, Escriou, Desprès, Jacob, Munier-Lehmann, Tangy, Vidalain: "Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity." in: PLoS pathogens, Vol. 9, Issue 10, pp. e1003678, (2013) (PubMed).

Hail, Chen, Kepa, Bushman, Shearn: "Dihydroorotate dehydrogenase is required for N-(4-hydroxyphenyl)retinamide-induced reactive oxygen species production and apoptosis." in: Free radical biology & medicine, Vol. 49, Issue 1, pp. 109-16, (2010) (PubMed).

Ng, Buckingham, Lee, Bigham, Tabor, Dent, Huff, Shannon, Jabs, Nickerson, Shendure, Bamshad: "Exome sequencing identifies the cause of a mendelian disorder." in: Nature genetics, Vol. 42, Issue 1, pp. 30-5, (2009) (PubMed).

Grabar, Rozman, Logar, Praprotnik, Dolzan: "Dihydroorotate dehydrogenase polymorphism influences the toxicity of leflunomide treatment in patients with rheumatoid arthritis." in: Annals of the rheumatic diseases, Vol. 68, Issue 8, pp. 1367-8, (2009) (PubMed).

Pawlik, Herczynska, Kurzawski, Safranow, Dziedziejko, Drozdzik: "The effect of exon (19C>A) dihydroorotate dehydrogenase gene polymorphism on rheumatoid arthritis treatment with leflunomide." in: Pharmacogenomics, Vol. 10, Issue 2, pp. 303-9, (2009) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Synonyms and alternative names related to DHODH

dihydroorotate dehydrogenase (quinone) (DHODH), dihydroorotate dehydrogenase (Dhodh), dihydroorotate dehydrogenase (quinone) (Dhodh), dihydroorotate dehydrogenase (pyrD), dihydroorotate dehydrogenase (pyr4), dihydroorotate dehydrogenase (Mrub_0263), dihydroorotate dehydrogenase (Arnit_2124), dihydroorotate dehydrogenase (Trad_2703), dihydroorotate dehydrogenase (Ftrac_1484), dihydroorotate dehydrogenase (Ndas_0799), dihydroorotate dehydrogenase (Mesil_1876), dihydroorotate dehydrogenase (Slip_0841), dihydroorotate dehydrogenase (Spirs_1436), dihydroorotate dehydrogenase (quinone) (XFHB_RS12780), dihydroorotate dehydrogenase (quinone) L homeolog (dhodh.L), 2810417D19Rik, AI834883, DDBDRAFT_0167009, DDBDRAFT_0185217, DDB_0167009, DDB_0185217, DHOD, DHODase, DHOdehase, dhodh, POADS, URA1, XFHB_12025

Protein level used designations for DHODH

  • dihydroorotate dehydrogenase (quinone), mitochondrial
  • dihydroorotate oxidase
  • human complement of yeast URA1
  • DHOdehase
  • dihydroorotate dehydrogenase, mitochondrial
  • dihydroorotate dehydrogenase
  • Dihydroorotate oxidase
  • dihydroorotate dehydrogenase (quinone) L homeolog
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