DUSP12 Proteins

(Dual Specificity Phosphatase 12 (DUSP12))

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008].

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7 results

DUSP12 Protein (AA 1-340) (His tag)

custom-made DUSP12 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant DUSP12 Protein, UniprotID Q9UNI6

3 images

Catalog No. ABIN7547264

Details

DUSP12 Protein (AA 1-339) (His tag)

custom-made DUSP12 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Dusp12 Protein, UniprotID Q9D0T2

3 images

Catalog No. ABIN7560853

Details

DUSP12 Protein (AA 1-340) (GST tag)

DUSP12 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

Image no. 1 for Dual Specificity Phosphatase 12 (DUSP12) (AA 1-340) protein (GST tag) (ABIN1352104)

1 image

Catalog No. ABIN1352104

Details

DUSP12 Protein (AA 1-339) (Strep Tag)

custom-made DUSP12 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3128827

Details

DUSP12 Protein (AA 1-340) (Strep Tag)

custom-made DUSP12 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3079207