DYST Protein (AA 1-195, partial) (His tag)
This Recombinant DYST protein is expressed in Yeast.
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Catalog No. ABIN5714422
$544.50
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Quick Overview for DYST Protein (AA 1-195, partial) (His tag) (ABIN5714422)
Target
DYST
(Dystocia (Maternal) (DYST))
Protein Type
Recombinant
Origin
Human
Source
Yeast
Application
SDS-PAGE (SDS)
Purity
Greater than 90 % as determined by SDS-PAGE.
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Protein Characteristics
- AA 1-195, partial
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Purification tag / Conjugate
- This DYST protein is labelled with His tag.
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Purpose
- Recombinant Human Dystonin(DST),partial
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Sequence
- MHSSSYSYRS SDSVFSNTTS TRTSLDSNEN LLLVHCGPTL INSCISFGSE SFDGHRLEML QQIANRVQRD SVICEDKLIL AGNALQSDSK RLESGVQFQN EAEIAGYILE CENLLRQHVI DVQILIDGKY YQADQLVQRV AKLRDEIMAL RNECSSVYSK GRILTTEQTK LMISGITQSL NSGFAQTLHP SLTSG
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Characteristics
- N-terminal 6xHis-tagged
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- Tris-based buffer50 % glycerol
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Storage
- -20 °C,-80 °C
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Storage Comment
- The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
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Expiry Date
- 6-12 months
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- DYST (Dystocia (Maternal) (DYST))
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Alternative Name
- DYST
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Background
- Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh.Isoform 3: plays a structural role in the assbly of hidesmosomes of epithelial cells, anchors keratin-containing intermediate filaments to the inner plaque of hidesmosomes. Required for the regulation of keratinocyte polarity and motility, mediates integrin ITGB4 regulation of RAC1 activity.Isoform 6: required for bundling actin filaments around the nucleus.Isoform 7: regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport.
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Molecular Weight
- 25.1 kDa
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Gene ID
- 667
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UniProt
- Q03001
Target
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