Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 3 (Xeroderma Pigmentosum Group B Complementing) (ERCC3) (N-Term) Peptide
ERCC3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target
- ERCC3 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 3 (Xeroderma Pigmentosum Group B Complementing) (ERCC3))
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MGKRDRADRD KKKSRKRHYE DEEDDEEDAP GNDPQEAVPS AAGKQVDESG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ERCC3 Antibody(ARP37963_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- ERCC3 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 3 (Xeroderma Pigmentosum Group B Complementing) (ERCC3))
- Background
-
ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.
Alias Symbols: BTF2, GTF2H, RAD25, TFIIH, XPB
Protein Interaction Partner: CCND1,IRF1,TAF7,TP53,BCR,CCNH,CDK7,ERCC2,GTF2E1,GTF2E2,GTF2H1,GTF2H2,GTF2H3,GTF2H4,GTF2H5,MNAT1,PSMC5,RAD52,TP53,XPC,ATF7IP,BCR,CCNH,CDK7,ERCC2,ERCC5,GCN1L1,GTF2E1,GTF2E2,GTF2H1,GTF2H2,GTF2H3,GTF2H4,GTF2H5,MNAT1,PSMC5,TP53,XPC,ZSCAN1
Protein Size: 782 - Molecular Weight
- 89 kDa
- Gene ID
- 2071
- NCBI Accession
- NM_000122, NP_000113
- UniProt
- P19447
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