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EXOSC4 Proteins

(Exosome Component 4 (EXOSC4))
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC4 binds to ARE-containing RNAs (By similarity).
EXOSC4 Protein (AA 1-100) (GST tag) EXOSC4 Protein (AA 1-100) (GST tag) EXOSC4 Protein (AA 1-100) (GST tag) (ABIN1353242)

EXOSC4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

EXOSC4 Protein (AA 1-245) (GST tag) EXOSC4 Protein (AA 1-245) (GST tag) EXOSC4 Protein (AA 1-245) (GST tag) (ABIN1353240)

EXOSC4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

EXOSC4 Protein (AA 2-245) (His tag) EXOSC4 Protein (AA 2-245) (His tag) EXOSC4 Protein (AA 2-245) (His tag) (ABIN3092480)

Crystallography grade EXOSC4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys

EXOSC4 Proteins by Grade

Find EXOSC4 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

EXOSC4 Proteins by Origin

Find EXOSC4 Proteins for a variety of species such as anti-Human EXOSC4, anti-Cow EXOSC4, anti-Mouse EXOSC4. The species listed below are among those available. Click on a link to go to the corresponding products.

EXOSC4 Proteins by Source

Here you will find EXOSC4 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

EXOSC4 Proteins by Protein Type

Here you can find EXOSC4 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

EXOSC4 Proteins by Application

Find EXOSC4 Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular EXOSC4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353242
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353240
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3092480
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136870
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5853354
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1678234
Quantity 1 mg
Datasheet Datasheet

Aliases for EXOSC4 Proteins

exosome component 4 (exosc4) Proteins
exosome component 4 (EXOSC4) Proteins
exosome component 4 (CC1G_03561) Proteins
exosome component 4 S homeolog (exosc4.S) Proteins
exosome component 4 (Exosc4) Proteins
1110039I09Rik Proteins
1500001N04Rik Proteins
EXOSC4 Proteins
hRrp41p Proteins
p12A Proteins
RRP41 Proteins
Rrp41 Proteins
RRP41A Proteins
Rrp41p Proteins
SKI6 Proteins
Ski6p Proteins
zgc:73175 Proteins
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