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neonatal Fc Receptor Proteins

(neonatal Fc Receptor (FcRn))
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

36 results

FcRn Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Catalog No. ABIN7583297
$456.18
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 3 to 5 Business Days
 
FcRn Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN2115488
$475.80
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Will be delivered in 4 Business Days
 
FcRn Origin: Mouse Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
Catalog No. ABIN7678672
$600.74
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 12 to 14 Business Days
 
FcRn Origin: Human Host: HEK-293 Cells Recombinant > 97 % by SDS-PAGE. Active
Catalog No. ABIN7534672
$533.50
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 7 to 9 Business Days
 
FcRn Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Catalog No. ABIN7504325
$715.42
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 3 to 5 Business Days
 
FcRn Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
Catalog No. ABIN7403297
$785.85
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
FcRn Origin: Pig Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func
Catalog No. ABIN4949195
$388.46
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Will be delivered in 5 Business Days
 
FcRn Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5709509
$488.40
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Will be delivered in 11 Business Days
 
FcRn Origin: Human Host: Yeast Recombinant > 90 % SDS
Catalog No. ABIN5713450
$544.50
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 11 Business Days
 
FcRn Origin: Cynomolgus Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5711682
$829.40
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Will be delivered in 11 Business Days
 
FcRn Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2720990
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Will be delivered in 11 Business Days
 
FcRn Origin: Cynomolgus Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1643585
$3,258.20
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 71 Business Days
 
FcRn Origin: Human Host: Bacteria Recombinant
Catalog No. ABIN7816356
$520.52
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to: United States
Delivery in 7 to 8 Business Days
 
FcRn Origin: Mouse Host: Bacteria Recombinant
Catalog No. ABIN7819986
$520.52
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to: United States
Delivery in 7 to 8 Business Days
 
FcRn Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2720991
$402.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
Shipping to: United States
Delivery in 4 to 8 Business Days
 
FcRn Origin: Rat Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1473931
$3,267.00
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 71 Business Days
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • ELISA
    • Western Blotting (WB)
    • Antibody Production (AbP)
    • Standard (STD)
    • Immunogen (Imm)
    • Size-exclusion chromatography-High Pressure Liquid Chromatography (SEC-HPLC)
    • Surface Plasmon Resonance (SPR)
    • Activity Assay (AcA)
    • Affinity Measurement (AM)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Immunoassay (IA)
    • Positive Control (PC)
    • Screening Assay (ScA)
    • Antibody Drug Assay (ADA)
  • Reactivity
    • Human
    • Mouse
    • Cynomolgus
    • Rat
    • Rhesus Monkey
    • Pig
  • Cited in publications
  • Images available
  • Preservative free only
  • Carrier free only
  • Host
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Yeast
    • Bacteria
    • Mammalian Cells
    • Baculovirus infected Insect Cells
    • Human Cells
    • Wheat germ
  • Binding Specificity
    • AA 24-297
    • AA 22-297
    • AA 23-298
    • Extracellular
    • AA 24-365
    • Transcript Variant 2
    • AA 16-289
    • AA 21-119
    • AA 22-301
    • AA 24-290
    • AA 25-292
    • AA 51-160
    • Transcript Variant 1
  • Conjugate
    • His tag
    • His tag,Strep Tag
    • His tag,Strep Tag,AVI tag,Biotin
    • GST tag
    • Myc-DYKDDDDK Tag
    • Un-conjugated
    • Biotin,His-Avi Tag
    • His tag,AVI tag,Strep Tag,Biotin
    • His tag,Strep Tag,Biotin
    • His-Avi Tag
    • His-Avi Tag,Biotin
    • His-SUMO Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • OriGene
    • Signalway
    • CUSABIO
    • ProteoGenix

Latest Publications for our neonatal Fc Receptor Proteins

Spencer, Goldberg, Pandey, Ordonez, Dufloo, Barnette, Sutton, Henderson, Agnor, Gao, Bruel, Schwartz, Haigwood, Ackerman, Hessell: "Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis." in: Nature communications, Vol. 13, Issue 1, pp. 662, (2022) (PubMed).

Kisalu, Pereira, Ernste, Flores-Garcia, Idris, Asokan, Dillon, MacDonald, Shi, Chen, Pegu, Schön, Zavala, Balazs, Francica, Seder: "Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention." in: JCI insight, Vol. 6, Issue 3, (2021) (PubMed).

Asokan, Dias, Liu, Maximova, Ernste, Pegu, McKee, Shi, Chen, Almasri, Promsote, Ambrozak, Gama, Hu, Douek, Todd, Lifson, Fourati, Sekaly, Crowley, Ackerman, Ko, Kilam, Boritz, Liao, Best, Perelson et al.: "Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Issue 31, pp. 18754-18763, (2020) (PubMed).

Zhao, Gao, Yu, Li, Zhang, Zhang, Lu, Gao, Guo: "Unidirectional transport of IgG by neonatal Fc receptor in human thyrocytes varies across different IgG subclasses." in: Molecular and cellular endocrinology, Vol. 477, pp. 103-111, (2019) (PubMed).

Simonov, Ivanov, Smolov, Abbasova, Piskunov, Poteryaev: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).

Yang, Kim, Seong, Tae, Kwon: "Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin." in: Biomaterials science, Vol. 6, Issue 8, pp. 2092-2100, (2018) (PubMed).

Kenniston, Taylor, Conley, Cosic, Kopacz, Lindberg, Comeau, Atkins, Bullen, TenHoor, Adelman, Sexton, Edwards, Nixon: "Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody." in: The Journal of biological chemistry, Vol. 292, Issue 42, pp. 17449-17460, (2017) (PubMed).

Zhou, Wang, Tong, Okamoto, Shen, Zaro: "Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery." in: Biomaterials, Vol. 117, pp. 24-31, (2017) (PubMed).

Fan, Neubert: "Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS." in: Analytical chemistry, Vol. 88, Issue 8, pp. 4239-47, (2016) (PubMed).

Deissler, Lang, Lang: "Internalization of bevacizumab by retinal endothelial cells and its intracellular fate: Evidence for an involvement of the neonatal Fc receptor." in: Experimental eye research, Vol. 143, pp. 49-59, (2015) (PubMed).

Aliases for neonatal Fc Receptor Proteins

Fc fragment of IgG receptor and transporter (FCGRT) Proteins
Fc fragment of IgG receptor and transporter (Fcgrt) Proteins
Fc receptor, IgG, alpha chain transporter (Fcgrt) Proteins
alpha-chain Proteins
FCRN Proteins
FcRn Proteins
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