FE65 Proteins

(Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))

The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012].

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FE65 Protein (AA 1-710) (His tag)

custom-made APBB1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant APBB1 Protein, UniprotID O00213

3 images

Catalog No. ABIN7552195

Details

FE65 Protein (AA 1-710) (His tag)

custom-made APBB1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Apbb1 Protein, UniprotID Q9QXJ1

3 images

Catalog No. ABIN7565148

Details

FE65 Protein (AA 1-708) (GST tag)

APBB1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

Image no. 1 for Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1) (AA 1-708) protein (GST tag) (ABIN1345278)

1 image

Catalog No. ABIN1345278

Details

FE65 Protein (AA 1-710) (Strep Tag)

custom-made APBB1 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3137376

Details

FE65 Protein (AA 1-710) (Strep Tag)

custom-made APBB1 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3089042