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Glycocalicin Products

(Glycocalicin (GC))

Categories

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010].

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Recommended Glycocalicin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7437521
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN2621449
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
Cat. No. ABIN1174955
Quantity 200 μL
Datasheet Datasheet

Recommended Glycocalicin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6956247
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962011
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN509809
Quantity 96 tests
Datasheet Datasheet

Recommended Glycocalicin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7402409
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3009655
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Glycocalicin products

Shen, Zhang, Feng, Chen, Li, Iqbal, Liao, Zhao, Zhai: "iTRAQ-Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism." in: Proteomics. Clinical applications, Vol. 12, Issue 3, pp. e1700085, (2019) (PubMed).

Tana, Zhao, Bradshaw, Moon, Page, Turner, Rivera, Kleiner, Heller: "Factors associated with the platelet count in patients with chronic hepatitis C." in: Thrombosis research, Vol. 135, Issue 5, pp. 823-8, (2015) (PubMed).

Haji-Valizadeh, Modery-Pawlowski, Sen Gupta: "A factor VIII-derived peptide enables von Willebrand factor (VWF)-binding of artificial platelet nanoconstructs without interfering with VWF-adhesion of natural platelets." in: Nanoscale, Vol. 6, Issue 9, pp. 4765-73, (2014) (PubMed).

Synonyms and alternative names related to Glycocalicin

glycoprotein Ib platelet alpha subunit (GP1BA), glucagon (GCG), BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GLP1, GLP2, GP1B, GPIbA, GRPP, VWDP

Protein level used designations for Glycocalicin

  • GP-Ib alpha
  • antigen CD42b-alpha
  • platelet glycoprotein Ib alpha chain
  • platelet membrane glycoprotein 1b-alpha subunit
  • glicentin-related polypeptide
  • glucagon-like peptide 1
  • glucagon-like peptide 2
  • preproglucagon
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