GUT2 Protein (AA 43-600) (His tag)
This Recombinant GUT2 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN1001067
Quick Overview for GUT2 Protein (AA 43-600) (His tag) (ABIN1001067)
Target
GUT2
(Mitochondrial Glycerol-3-Phosphate Dehydrogenase (GUT2))
Protein Type
Recombinant
Origin
Human
Source
Escherichia coli (E. coli)
Application
Western Blotting (WB), Control (Ct)
Purity
> 95 %
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Protein Characteristics
- AA 43-600
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Purification tag / Conjugate
- This GUT2 protein is labelled with His tag.
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Purpose
- Mitochondrial Glycerol-3-Phosphate Dehydrogenase (mGPD) (Western Blot Control)
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Sequence
- ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS VQAAEEALPR IVELMGRELN WDDYKKQEQL ETARKFLY
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Characteristics
- recombinant mGPD comprises a 558 amino acid fragment (43-600) corresponding to the GlpA domain fragment of the mature mGPD protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied in 1x Laemmli Buffer (25 mM Tris-HCl pH 6.8, 50 mM DTT, 1 % (w/v) SDS, 0.1 % (w/v) Bromophenol Blue, 2.5 % Glycerol).
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Preservative
- Dithiothreitol (DTT)
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Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C
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- GUT2 (Mitochondrial Glycerol-3-Phosphate Dehydrogenase (GUT2))
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Alternative Name
- Mitochondrial Glycerol-3-Phosphate Dehydrogenase
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Background
- Mitochondrial glycerol-3-phosphate dehydrogenase (mGPD) is a Ca2+ -sensitive, FAD-binding protein, located on the outer surface of the inner mitochondrial membrane. mGPD catalyses the oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Two isoforms have been described for mGPD. Isoform 1 comprises 727aa residues, whereas isoform 2 lacks 126aa residues of the N-terminus. Deficiency of mGPD appears to contribute to the impairment of glucose-stimulated insulin release in several animal models of non-insulin dependent diabetes mellitus.,Glycerol-3-Phosphate Dehydrogenase 2, GPD2, Glycerophosphate Dehydrognase-2 Ca(2+ ) - Responsive Mitochondrial FAD-Linked, Mitochondrial GPD, GPDM, GPD-M, GPDH-M, mtGPD, GDH2.
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Molecular Weight
- 66.26 kDa
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UniProt
- P43304
Target
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