HDAC3 Products
(Histone Deacetylase 3 (HDAC3))
Categories
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008].
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Featured HDAC3 Categories
HDAC3 Antibodies
High quality antibodies with extensive validation data.
HDAC3 ELISA Kits
Reliable ELISA kits for a wide range of species.
HDAC3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HDAC3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP, ChIP
Validations
- (3)
- (9)
Cat. No.
ABIN3023018
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (6)
Cat. No.
ABIN6262179
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (9)
Cat. No.
ABIN6256332
Quantity
100 μL
Datasheet
Datasheet
Recommended HDAC3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967438
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967437
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967436
Quantity
96 tests
Datasheet
Datasheet
Recommended HDAC3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1306448
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306450
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3132256
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our HDAC3 products
: "A Novel ZIP4-HDAC4-VEGFA Axis in High-Grade Serous Ovarian Cancer." in: Cancers, Vol. 13, Issue 15, (2021) (PubMed).: "Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription." in: Cell research, Vol. 27, Issue 7, pp. 898-915, (2018) (PubMed).
: "Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3." in: The Journal of biological chemistry, Vol. 291, Issue 12, pp. 6316-30, (2016) (PubMed).
: "Immunohistochemical Characterization of Histone Deacetylase as a Potential Prognostic Marker and Therapeutic Target in Endometrial Stromal Sarcoma." in: Anticancer research, Vol. 36, Issue 5, pp. 2527-34, (2016) (PubMed).
: "Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells." in: Journal of translational medicine, Vol. 14, pp. 7, (2016) (PubMed).
: "C/EBPα negatively regulates SIRT7 expression via recruiting HDAC3 to the upstream-promoter of hepatocellular carcinoma cells." in: Biochimica et biophysica acta, Vol. 1859, Issue 2, pp. 348-54, (2016) (PubMed).
: "Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon." in: Clinical epigenetics, Vol. 7, pp. 102, (2015) (PubMed).
: "Inhibition of HDAC3 promotes ligand-independent PPAR? activation by protein acetylation." in: Journal of molecular endocrinology, Vol. 53, Issue 2, pp. 191-200, (2014) (PubMed).
: "Class I HDACs are mediators of smoke carcinogen-induced stabilization of DNMT1 and serve as promising targets for chemoprevention of lung cancer." in: Cancer prevention research (Philadelphia, Pa.), Vol. 7, Issue 3, pp. 351-61, (2014) (PubMed).
: "Differential effect of HDAC3 on cytoplasmic and nuclear huntingtin aggregates." in: PLoS ONE, Vol. 9, Issue 11, pp. e111277, (2014) (PubMed).
Synonyms and alternative names related to HDAC3
Histone deacetylase 3 (HDAC3), histone deacetylase 3 (hdac3), histone deacetylase 3 (CNL05260), histone deacetylase 3 (HDAC3), histone deacetylase 3 (Hdac3), histone deacetylase 3 S homeolog (hdac3.S), AW537363, CG2128, DHDAC3, dHDAC3, Dmel\\CG2128, dmHDA402, DmHDAC3, Dromel_CG2128_FBtr0078767_hdac3_mORF, hd3, HD3, HDAC, HDAC3, Hdac 3, hdac3, HDm, RPD3, rpd3-2, RPD3-2, XRpd3, zgc:55927Protein level used designations for HDAC3
- CG2128-PA
- Hdac3-PA
- histone Deacetylase-3
- histone deacetylase 3
- SMAP45
- HD3
- HDAC3 splicing HDAC3alpha
- HDAC3 splicing HDAC3beta
- HDAC3 splicing HDAC3delta
- HDAC3 splicing HDAC3gamma
- histone deacetylase-3
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