The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Feb 2009].
custom-made
HOPX
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
HOPX
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Wahyudi, Wang, McAlpine: "Dimerization of a heat shock protein 90 inhibitor enhances inhibitory activity." in: Organic & biomolecular chemistry, Vol. 12, Issue 5, pp. 765-73, (2014) (PubMed).
Willmer, Contu, Blatch, Edkins: "Knockdown of Hop downregulates RhoC expression, and decreases pseudopodia formation and migration in cancer cell lines." in: Cancer letters, Vol. 328, Issue 2, pp. 252-60, (2012) (PubMed).
Aliases for HOPX Proteins
HOP homeobox (HOPX) Proteins HOP homeobox (Hopx) Proteins HOP homeobox (hopx) Proteins 1110018K11Rik Proteins 1200015P04Rik Proteins 2300002F06Rik Proteins AI848177 Proteins AW490897 Proteins CAMEO Proteins Cameo Proteins cameo Proteins GIIg15b Proteins Hdop Proteins HOD Proteins Hod Proteins hod Proteins HOP Proteins Hop Proteins hop Proteins HOPX Proteins LAGY Proteins lagy Proteins MGC147344 Proteins NECC1 Proteins necc1 Proteins OB1 Proteins Ob1 Proteins ob1 Proteins Obl Proteins SMAP31 Proteins smap31 Proteins TOTO Proteins Toto Proteins toto Proteins