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Hsc70 Proteins

(Heat Shock 70kDa Protein 8 (HSPA8))
This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

18 results

HSPA8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Pubmed 1 reference
Catalog No. ABIN1307208
-15% Promotion 2026
$415.41
$488.72
save $73.31 (-15 %)
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 12 Business Days
 
HSPA8 Origin: Human Host: Escherichia coli (E. coli) Recombinant >90% WB, SDS, ELISA, Func, AcA Active
Pubmed 6 references
Catalog No. ABIN1686679
-15% Promotion 2026
$413.31
$486.25
save $72.94 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 3 to 4 Business Days
 
HSPA8 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Catalog No. ABIN7123272
-15% Promotion 2026
$513.93
$604.62
save $90.69 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
HSPA8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN668046
-15% Promotion 2026
$732.31
$861.54
save $129.23 (-15 %)
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 19 Business Days
 
HSPA8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Catalog No. ABIN7397123
-15% Promotion 2026
$477.28
$561.51
save $84.23 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
HSPA8 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7397126
-15% Promotion 2026
$586.24
$689.70
save $103.46 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
HSPA8 Origin: Cow Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7400330
-15% Promotion 2026
$613.49
$721.75
save $108.26 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
HSPA8 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7404647
-15% Promotion 2026
$622.00
$731.77
save $109.77 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
HSPA8 Origin: Chicken Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Catalog No. ABIN7400333
-15% Promotion 2026
$640.73
$753.80
save $113.07 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
HSPA8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317575
-15% Promotion 2026
$883.32
$1,039.20
save $155.88 (-15 %)
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
HSPA8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
Catalog No. ABIN2129788
-15% Promotion 2026
$1,717.19
$2,020.22
save $303.03 (-15 %)
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 9 to 11 Business Days
 
HSPA8 Origin: Cow Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Catalog No. ABIN3009779
$796.06
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 18 Business Days
 
HSPA8 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Catalog No. ABIN3009781
$796.06
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 18 Business Days
 
HSPA8 Origin: Chicken Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Catalog No. ABIN3009780
$826.86
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 18 Business Days
 
HSPA8 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2723109
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Will be delivered in 11 Business Days
 
HSPA8 Origin: Human Host: Bacteria Recombinant
Catalog No. ABIN7816886
$520.52
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to: United States
Delivery in 7 to 8 Business Days
 
HSPA8 Origin: Rat Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7584760
$2,065.80
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 71 Business Days
 
HSPA8 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Catalog No. ABIN6305097
$565.06
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 16 Business Days
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Immunoprecipitation (IP)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Standard (STD)
  • Reactivity
    • Human
    • Rat
    • Chicken
    • Cow
    • Mouse
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • Bacteria
    • HEK-293 Cells
    • Wheat germ
    • Yeast
  • Binding Specificity
    • AA 534-615
    • AA 1-646
    • AA 2-646
    • AA 359-646
    • Transcript Variant 1
  • Conjugate
    • His tag
    • Un-conjugated
    • GST tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
  • Supplier
    • antibodies-online
    • Abbexa
    • CUSABIO
    • OriGene
    • ProteoGenix

Latest Publications for our Hsc70 Proteins

Zhou, Cui, Hu, Wen, Du, Du: "Identification of a novel anti‑heat shock cognate 71 kDa protein antibody in patients with Kawasaki disease." in: Molecular medicine reports, Vol. 21, Issue 4, pp. 1771-1778, (2020) (PubMed).

Liu, Vielhauer, Holzbeierlein, Zhao, Ghosh, Brown, Lee, Blagg: "KU675, a Concomitant Heat-Shock Protein Inhibitor of Hsp90 and Hsc70 that Manifests Isoform Selectivity for Hsp90α in Prostate Cancer Cells." in: Molecular pharmacology, Vol. 88, Issue 1, pp. 121-30, (2015) (PubMed).

Kimura, Yoshikura, Koumura, Hayashi, Kobayashi, Kobayashi, Yano, Inuzuka: "Identification of target antigens of naturally occurring autoantibodies in cerebrospinal fluid." in: Journal of proteomics, (2015) (PubMed).

Ravindran, Bagchi, Inoue, Tsai: "A Non-enveloped Virus Hijacks Host Disaggregation Machinery to Translocate across the Endoplasmic Reticulum Membrane." in: PLoS pathogens, Vol. 11, Issue 8, pp. e1005086, (2015) (PubMed).

Thirunavukarasu, Shi: "An RNA aptamer specific to Hsp70-ATP conformation inhibits its ATPase activity independent of Hsp40." in: Nucleic acid therapeutics, Vol. 25, Issue 2, pp. 103-12, (2015) (PubMed).

Heimdal, Sanchez-Guixé, Aukrust, Bollerslev, Bruland, Jablonski, Erichsen, Gude, Koht, Erdal, Fiskerstrand, Haukanes, Boman, Bjørkhaug, Tallaksen, Knappskog, Johansson: "STUB1 mutations in autosomal recessive ataxias - evidence for mutation-specific clinical heterogeneity." in: Orphanet journal of rare diseases, Vol. 9, pp. 146, (2014) (PubMed).

Fujiwara, Furuta, Kikuchi, Aizawa, Hatanaka, Konya, Uchida, Yoshimura, Tamai, Wada, Kabuta: "Discovery of a novel type of autophagy targeting RNA." in: Autophagy, Vol. 9, Issue 3, pp. 403-9, (2013) (PubMed).

Chow, Mok, Xiao, Khalouei, Brown: "Heteromeric complexes of heat shock protein 70 (HSP70) family members, including Hsp70B', in differentiated human neuronal cells." in: Cell stress & chaperones, Vol. 15, Issue 5, pp. 545-53, (2010) (PubMed).

Takino, Kobayashi, Takeuchi: "The formation of intracellular glyceraldehyde-derived advanced glycation end-products and cytotoxicity." in: Journal of gastroenterology, Vol. 45, Issue 6, pp. 646-55, (2010) (PubMed).

Zwang, Hoffert, Pisitkun, Moeller, Fenton, Knepper: "Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry." in: Journal of proteome research, Vol. 8, Issue 3, pp. 1540-54, (2009) (PubMed).

Aliases for Hsc70 Proteins

heat shock protein family A (Hsp70) member 8 L homeolog (hspa8.L) Proteins
heat shock protein family A (Hsp70) member 8 (HSPA8) Proteins
heat shock protein family A (Hsp70) member 8 (Hspa8) Proteins
heat shock 70kDa protein 8 (HSPA8) Proteins
heat shock protein 8 (Hspa8) Proteins
heat shock protein 8 (hspa8) Proteins
2410008N15Rik Proteins
hsc54 Proteins
HSC54 Proteins
hsc70 Proteins
HSC70 Proteins
Hsc70 Proteins
hsc71 Proteins
HSC71 Proteins
Hsc71 Proteins
Hsc73 Proteins
hsp71 Proteins
HSP71 Proteins
hsp73 Proteins
HSP73 Proteins
Hsp73 Proteins
hspa10 Proteins
HSPA10 Proteins
Hspa10 Proteins
lap1 Proteins
LAP1 Proteins
nip71 Proteins
NIP71 Proteins
wu:fb01g06 Proteins
wu:fi48b06 Proteins
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