Hsc70 Proteins
(Heat Shock 70kDa Protein 8 (HSPA8))
This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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19 results
HSPA8
Origin: Human
Host: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
1 reference
HSPA8
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
>90%
WB, SDS, ELISA, Func, AcA
Active
6 references
HSPA8
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
HSPA8
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS-PAGE
SDS
1 image
HSPA8
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
HSPA8
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
HSPA8
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
HSPA8
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
HSPA8
Origin: Cow
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
HSPA8
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
HSPA8
Origin: Chicken
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
HSPA8
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 90 % as determined by reducing SDS-PAGE.
HSPA8
Origin: Cow
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
HSPA8
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
HSPA8
Origin: Chicken
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
HSPA8
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
HSPA8
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
Latest Publications for our Hsc70 Proteins
: "Identification of a novel anti‑heat shock cognate 71 kDa protein antibody in patients with Kawasaki disease." in: Molecular medicine reports, Vol. 21, Issue 4, pp. 1771-1778, (2020) (PubMed).: "KU675, a Concomitant Heat-Shock Protein Inhibitor of Hsp90 and Hsc70 that Manifests Isoform Selectivity for Hsp90α in Prostate Cancer Cells." in: Molecular pharmacology, Vol. 88, Issue 1, pp. 121-30, (2015) (PubMed).
: "Identification of target antigens of naturally occurring autoantibodies in cerebrospinal fluid." in: Journal of proteomics, (2015) (PubMed).
: "A Non-enveloped Virus Hijacks Host Disaggregation Machinery to Translocate across the Endoplasmic Reticulum Membrane." in: PLoS pathogens, Vol. 11, Issue 8, pp. e1005086, (2015) (PubMed).
: "An RNA aptamer specific to Hsp70-ATP conformation inhibits its ATPase activity independent of Hsp40." in: Nucleic acid therapeutics, Vol. 25, Issue 2, pp. 103-12, (2015) (PubMed).
: "STUB1 mutations in autosomal recessive ataxias - evidence for mutation-specific clinical heterogeneity." in: Orphanet journal of rare diseases, Vol. 9, pp. 146, (2014) (PubMed).
: "Discovery of a novel type of autophagy targeting RNA." in: Autophagy, Vol. 9, Issue 3, pp. 403-9, (2013) (PubMed).
: "Heteromeric complexes of heat shock protein 70 (HSP70) family members, including Hsp70B', in differentiated human neuronal cells." in: Cell stress & chaperones, Vol. 15, Issue 5, pp. 545-53, (2010) (PubMed).
: "The formation of intracellular glyceraldehyde-derived advanced glycation end-products and cytotoxicity." in: Journal of gastroenterology, Vol. 45, Issue 6, pp. 646-55, (2010) (PubMed).
: "Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry." in: Journal of proteome research, Vol. 8, Issue 3, pp. 1540-54, (2009) (PubMed).
Aliases for Hsc70 Proteins
heat shock protein family A (Hsp70) member 8 L homeolog (hspa8.L) Proteinsheat shock protein family A (Hsp70) member 8 (HSPA8) Proteins
heat shock protein family A (Hsp70) member 8 (Hspa8) Proteins
heat shock 70kDa protein 8 (HSPA8) Proteins
heat shock protein 8 (Hspa8) Proteins
heat shock protein 8 (hspa8) Proteins
2410008N15Rik Proteins
hsc54 Proteins
HSC54 Proteins
hsc70 Proteins
HSC70 Proteins
Hsc70 Proteins
hsc71 Proteins
HSC71 Proteins
Hsc71 Proteins
Hsc73 Proteins
hsp71 Proteins
HSP71 Proteins
hsp73 Proteins
HSP73 Proteins
Hsp73 Proteins
hspa10 Proteins
HSPA10 Proteins
Hspa10 Proteins
lap1 Proteins
LAP1 Proteins
nip71 Proteins
NIP71 Proteins
wu:fb01g06 Proteins
wu:fi48b06 Proteins
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