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Influenza A H1N1 PB1 antibody (C-Term)

PB1 Reactivity: Influenza A Virus H1N1 WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1574132
  • Target
    Influenza A H1N1 PB1 (PB1) (Influenza Polymerase Basic 1 (PB1))
    Binding Specificity
    C-Term
    Reactivity
    Influenza A Virus H1N1
    Host
    Rabbit
    Clonality
    Polyclonal
    Application
    Western Blotting (WB)
    Specificity
    H1N1 PB1 Antibody detects influenza A (H1N1) PB1 protein.
    Purification
    Immunoaffinity chromatography
    Immunogen
    KLH-coupled synthetic peptide from C-terminal of Influenza A (H1N1) 2009 virus PB1 protein (GenBank: CY040005).
    Isotype
    IgG
  • Application Notes
    Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
    Western blot: 0.5-1 µg/mL.Other Applications: user optimized.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4, containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Storage
    4 °C/-20 °C
    Storage Comment
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
  • Liedmann, Hrincius, Guy, Anhlan, Dierkes, Carter, Wu, Staeheli, Green, Wolff, McCullers, Ludwig, Ehrhardt: "Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions." in: Nature communications, Vol. 5, pp. 5645, (2014) (PubMed).

  • Target
    Influenza A H1N1 PB1 (PB1) (Influenza Polymerase Basic 1 (PB1))
    Alternative Name
    H1N1 PB1
    Synonyms
    polymerase PB1 antibody, PB1 antibody
    Target Type
    Influenza Protein
    Background
    Influenza A (H1N1) virus is a subtype of influenzavirus A and it is the most common cause of influenza (flu) in humans. A strain of swine-origin H1N1 was responsible for the 2009 flu pandemic. Influenza RNA-dependent RNA polymerase is composed of three subunits PB1, PA, and PB2. PB1 is the core of the complex and accounts for the polymerase activity. H1N1 PB1 Antibody is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of Influenza A (H1N1) 2009 virus PB1 protein (GenBank: CY040005).
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