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Verapamil HCl

BR, Inh 152-11-4 2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile hydrochloride (1:1)
Catalog No. ABIN1027891
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Quick Overview for Verapamil HCl (ABIN1027891)

Application

Blocking Reagent (BR), Inhibition (Inh)

Chemical Name

2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile hydrochloride (1:1)
  • Purpose

    L-type Ca channel blocker

    Characteristics

    L-type Ca channel blocker.

    Purity

    >98 %

    Formula

    C27H38N2O4•HCl

    Solubility

    Soluble to 100 mM in ethanol and to 50 mM in water
  • Comment

    Source: Synthetic.
    Appearance: White Solid

    Restrictions

    For Research Use only
  • Format

    Solid

    Precaution of Use

    Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R23/24/25 - Toxic by inhilation, in contact with skin and if swallowed R60 - May impair fertility R61 - May cause harm to the unborn child R68 - Possible risk of irreversible effects Hazard Phrases: H301-H311-H331 Precautionary Phrases: P261-P280-P301 + P310-P311

    Handling Advice

    Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R23/24/25 - Toxic by inhilation, in contact with skin and if swallowed R60 - May impair fertility R61 - May cause harm to the unborn child R68 - Possible risk of irreversible effects Hazard Phrases: H301-H311-H331 Precautionary Phrases: P261-P280-P301 + P310-P311

    Storage

    -20 °C
  • Background

    Verapamil is an L-type calcium channel blocker of the phenylalkylamine class. It has been used in the treatment of hypertension, angina pectoris, cardiac arrhythmia, and cluster headaches. Its mechanism is to block voltage-dependent calcium channels.

    Molecular Weight

    491.07

    CAS-No

    152-11-4
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