For best experience we recommend to activate Javascript in your browser.

Dofetilide

BR, Inh 115256-11-6 N-(4-{2-[Methyl(2-{4-[(methylsulfonyl)amino]phenoxy}ethyl)amino]ethyl}phenyl)methanesulfonamide, Tikosyn, UK 68798

Catalog No. ABIN1027897

$268.75

Plus shipping costs $50.00

Shipping to: United States

Delivery in 3 to 5 Business Days

Quick Overview for Dofetilide (ABIN1027897)

Application

Blocking Reagent (BR), Inhibition (Inh)

Chemical Name

N-(4-{2-[Methyl(2-{4-[(methylsulfonyl)amino]phenoxy}ethyl)amino]ethyl}phenyl)methanesulfonamide, Tikosyn, UK 68798

Purpose

Herg channel blocker

Characteristics

Herg channel blocker.

Purity

>98 %

Formula

C19H27N3O5S2

Solubility

Soluble to 100 mM in DMSO
Geldanamycin- FITC
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Radicicol
Inh 12772-57-5

Geldanamycin- Biotin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Herbimycin A
Inh 70563-58-5 [(2R,3S,5S,6R,7S,8E,10S,11S,12E,14E)-2,5,6,11-tetramethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate

17-GMB-APA-GA
Inh [(3R,5S,6R,7S,10S,11S)-21-[3-[4-(2,5-dioxopyrrol-1-yl)butanoylamino]propylamino]-6-hydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate

TEMPO
Inh 2564-83-2 2,2,6,6-Tetramethylpiperidine 1-oxyl, 2,2,6,6-Tetramethyl-1-piperidinyloxy, free radical, (2,2,6,6-Tetramethyl-1-piperidinyl)oxidanyl, 1,1,5,5-tetramethylpentamethylene nitroxide, 2,2,6,6-Tetramethylpiperidine-1-oxyl

Triacsin C
Inh 76896-80-5 (3E)-1-Oxo-3-[(2E,4E,7E)-2,4,7-undecatrien-1-ylidene]triazane

TPCK
Inh 402-71-1 N-(4-Chloro-3-oxo-1-phenyl-2-butanyl)-4-methylbenzenesulfonamide

Staurosporine
Inh 62996-74-1 (2S,3R,4R,6R)-3-Methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one

Comment

Source: Synthetic.
Appearance: White Solid

Restrictions

For Research Use only
Format

Solid

Precaution of Use

Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S53 - Avoid exposure - obtain special instruction before use S57 - Use appropriate containment to avoid environmental contamination Risk Phrases: R22 - Harmful if swallowed R48 - Danger of serious damage to health by prolonged exposure R51/53 - Toxic to aquatic organisms, may cause longterm adverse effects in the aquatic environment R61 - May cause harm to the unborn child R62 - Possible risk of impaired fertility Hazard Phrases: H302-H319-H360 Precautionary Phrases: P201-P305 + P351 + P338-P308 + P313

Handling Advice

Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S53 - Avoid exposure - obtain special instruction before use S57 - Use appropriate containment to avoid environmental contamination Risk Phrases: R22 - Harmful if swallowed R48 - Danger of serious damage to health by prolonged exposure R51/53 - Toxic to aquatic organisms, may cause longterm adverse effects in the aquatic environment R61 - May cause harm to the unborn child R62 - Possible risk of impaired fertility Hazard Phrases: H302-H319-H360 Precautionary Phrases: P201-P305 + P351 + P338-P308 + P313

Storage

-20 °C
Background

Dofetilide is a class III antiarrhythnic agent. It works by selectively blocking the rapid component of the delayed rectifier outward potassium current.
Synonyms: Tikosyn, UK 68798

Molecular Weight

441.56

CAS-No

115256-11-6