HPA (Hexyl-4-pentynoic acid)
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- Application
- Inhibition (Inh)
- Purpose
- HDAC inhibitor
- Characteristics
- Histone deacetylase (HDAC) inhibitor, IC50=13 μM. More potent and robust than valproic acid at inducing histone hyperacetylation (600 % at 50 μM), HSP70 induction and protection against glutamate excitotoxicity in cultured neurons. Cell permeable.
- Purity
- >98 %
- Chemical Name
- 2-(2-Propynyl)octanoic acid (racemic)
- Formula
- C11H18O2
- Permeability
- Cell-permeable
- Solubility
- Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
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Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
NicotinamideInh 98-92-0 Pyridine-3-carboxylic acid amide
5-AzacytidineInh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
SAHA (Vorinostat)Inh Cell-permeable 149647-78-9 Suberoylanilide-hydroxamic acid
Phenylbutyrate NaInh 1716-12-7 4-Phenylbutyric acid, sodium salt
CI-994Inh 112522-64-2 4-(Acetylamino)-N-(2-aminophenyl)benzamide
Tranylcypromine hemisulfate (±)Inh Cell-permeable 13492-01-8 Trans (±)-2-phenylcyclopropanamine, hemisulfate salt
Tenovin-1Inh 380315-80-0 N-[(4-Acetamidophenyl)carbamothioyl]-4-tert-butylbenzamide
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- Restrictions
- For Research Use only
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- Format
- Oil
- Storage
- RT
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- Background
- HPA,Epigenetics,Protein deacetylase,Posttranslational modification,Chromatin
- Molecular Weight
- 182.27
- CAS-No
- 96017-59-3
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