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Triacetylresveratrol

Act 42206-94-0 5-[(1E)-2-[4-(Acetyloxy)phenyl]ethenyl]-1,3-benzenediol-1,3-diacetate

/ (Triacetylresveratrol)

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Catalog No. ABIN7233301

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Quick Overview for Triacetylresveratrol (ABIN7233301)

Application

Activation (Act)

Chemical Name

5-[(1E)-2-[4-(Acetyloxy)phenyl]ethenyl]-1,3-benzenediol-1,3-diacetate

Purpose

SIRT activator, prodrug

Characteristics

A resveratrol prodrug. One method for increasing the half-life of resveratrol in vivo is acetylation of the phenolic OH groups. Deacetylation takes place in vivo or in intact cells via the action of intracellular esterases releasing active resveratrol. CWR22Rv1 cells when exposed to triacetyl resveratrol showed a G1S block concomitant with increased p53 and p21 expression1. In MCF-7 cells it induced both ERK and p38 phosphorylation2.

Purity

>98 %

Formula

C20H28O6

Solubility

Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 8 mg/ml).
Geldanamycin- FITC
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Radicicol
Inh 12772-57-5

Geldanamycin- Biotin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Herbimycin A
Inh 70563-58-5 [(2R,3S,5S,6R,7S,8E,10S,11S,12E,14E)-2,5,6,11-tetramethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate

17-GMB-APA-GA
Inh [(3R,5S,6R,7S,10S,11S)-21-[3-[4-(2,5-dioxopyrrol-1-yl)butanoylamino]propylamino]-6-hydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate

TEMPO
Inh 2564-83-2 2,2,6,6-Tetramethylpiperidine 1-oxyl, 2,2,6,6-Tetramethyl-1-piperidinyloxy, free radical, (2,2,6,6-Tetramethyl-1-piperidinyl)oxidanyl, 1,1,5,5-tetramethylpentamethylene nitroxide, 2,2,6,6-Tetramethylpiperidine-1-oxyl

Triacsin C
Inh 76896-80-5 (3E)-1-Oxo-3-[(2E,4E,7E)-2,4,7-undecatrien-1-ylidene]triazane

TPCK
Inh 402-71-1 N-(4-Chloro-3-oxo-1-phenyl-2-butanyl)-4-methylbenzenesulfonamide

Staurosporine
Inh 62996-74-1 (2S,3R,4R,6R)-3-Methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Powder

Storage

-20 °C

Storage Comment

-20°C
Background

3,5,4'-Tri-O-acetylresveratrol,NFkappaB,Epigenetics,Apoptosis inducer,Hedgehog,PI3K,Protein deacetylase,Antioxidant,Cell death,Immunology,Cancer,Diabetes,Ageing,Posttranslational modification,Inflammation,Chromatin

Molecular Weight

364.4

CAS-No

42206-94-0

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