For best experience we recommend to activate Javascript in your browser.

Chelerythrine chloride

Name: Chelerythrine chloride
SKU: ABIN7885754
Availability: InStock

3895-92-9 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride.

Molecular structure of ABIN7885754. (Chelerythrine chloride)

Dose-response curve of Chelerythrine chloride (ABIN7885754) inhibition of the 100 ng/mL Native mouse NGF 2. (Chelerythrine chloride)

BCA

Cells were incubated with different concentrations of Chelerythrine chloride (ABIN7885754) for 30 min and then stimulated with PMA (ABIN7885941), (3 ng/mL) for 20 min. (Chelerythrine chloride)

BCA

3 images

Catalog No. ABIN7885754

$251.85

Plus shipping costs $50.00

1 mg

Shipping to: United States

Delivery in 11 to 14 Business Days

Quick Overview for Chelerythrine chloride (ABIN7885754)

Chemical Name

1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride.

Reactivity

Macleaya Cordata

Host

Macleaya Cordata

Purpose

An Inhibitor of Protein Kinase C, SERCA Pump, and P2X7 Receptor

Specificity

Toxin target: PKC, SERCA pumps, P2X7 receptor

Characteristics

Chelerythrine chloride is a potent, cell-permeable inhibitor of protein kinase C (PKC). It is at least 100-fold more selective for PKCs than for other kinases1,2.

Purity

>99 %

Formula

C21H18ClNO4.

Solubility

Water or DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Thapsigargin
67526-95-8 (3S,3aR,4S,6S,6AR,7S,8S,9bS)-6-(Acetyloxy)-2,3,3a,4,5,6 ,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[ [(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutox y)azuleno[4,5-b]furan-7-yl octanoate.

K252a
97161-97-2 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, methyl ester, (9alpha,10beta,12alpha)-.

Geldanamycin- FITC
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Radicicol
Inh 12772-57-5

(±)-Bay K8644
71145-03-4 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl) phenyl]-3-pyridinecarboxylic acid, methyl ester.

Capsaicin
404-86-4 (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide.

K252b
99570-78-2 (9R,10S,12S)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid.

GS967
1262618-39-2 (6-[4-(trifluoromethoxy)phenyl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine)

GW-2580
870483-87-7 5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine.

Restrictions

For Research Use only
Format

Powder

Handling Advice

Centrifuge all product preparations before use (10000 x g 5 min).

Storage

-20 °C

Storage Comment

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Molecular Weight

383.84

CAS-No

3895-92-9