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Leptin Proteins

(Leptin (LEP))
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008].
Leptin Protein (LEP) (AA 22-167) (Fc Tag) Leptin Protein (LEP) (AA 22-167) (Fc Tag) Leptin Protein (LEP) (AA 22-167) (Fc Tag) (ABIN7275142)

LEP Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Leptin Protein (LEP) Leptin Protein (LEP) Leptin Protein (LEP) (ABIN5571245)

LEP Origin: Mouse Host: Escherichia coli (E. coli) Recombinant SDS, Func Active

Leptin Protein (LEP) Leptin Protein (LEP) Leptin Protein (LEP) (ABIN7320902)

LEP Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by reducing SDS-PAGE.

Leptin Proteins by Origin

Find Leptin Proteins for a variety of species such as anti-Human Leptin, anti-Mouse Leptin, anti-Rat Leptin. The species listed below are among those available. Click on a link to go to the corresponding products.

Leptin Proteins by Source

Here you will find Leptin Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Leptin Proteins by Protein Type

Here you can find Leptin Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Leptin Proteins by Application

Find Leptin Proteins validated for a specific application such as ELISA, SDS, WB, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Leptin Proteins by Biological Activity

Find Leptin Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular Leptin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275142
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN5571245
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7320902
Quantity 50 μg
Datasheet Datasheet
Reactivity Pig
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123746
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123742
Quantity 50 μg
Datasheet Datasheet
Reactivity Goldfish
Source Yeast
Validations
  • (1)
Cat. No. ABIN7321015
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123743
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309307
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5569843
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (4)
  • (1)
Cat. No. ABIN1047336
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2018192
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7318719
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1097077
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419637
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7520268
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Leptin Proteins

McNulty, Miller, OConnor, Guilak: "The effects of adipokines on cartilage and meniscus catabolism." in: Connective tissue research, Vol. 52, Issue 6, pp. 523-33, (2012) (PubMed).

Moon, Chamberland, Diakopoulos, Fiorenza, Ziemke, Schneider, Mantzoros: "Leptin and amylin act in an additive manner to activate overlapping signaling pathways in peripheral tissues: in vitro and ex vivo studies in humans." in: Diabetes Care, Vol. 34, Issue 1, pp. 132-8, (2011) (PubMed).

Zieba, Kirsz, Molik, Romanowicz, Wojtowicz: "Effects of orexigenic peptides and leptin on melatonin secretion during different photoperiods in seasonal breeding ewes: an in vitro study." in: Domestic animal endocrinology, Vol. 40, Issue 3, pp. 139-46, (2011) (PubMed).

Bouwman, Vreden, Hamdani, Wassenaar, Smeding, Loer, Stienen, Lamberts: "Effect of bupivacaine on sevoflurane-induced preconditioning in isolated rat hearts." in: European journal of pharmacology, Vol. 647, Issue 1-3, pp. 132-8, (2010) (PubMed).

Szczesna, Zieba, Klocek-Gorka, Misztal, Stepien: "Seasonal effects of central leptin infusion and prolactin treatment on pituitary SOCS-3 gene expression in ewes." in: The Journal of endocrinology, Vol. 208, Issue 1, pp. 81-8, (2010) (PubMed).

Roa, Garcia-Galiano, Varela, Sánchez-Garrido, Pineda, Castellano, Ruiz-Pino, Romero, Aguilar, López, Gaytan, Diéguez, Pinilla, Tena-Sempere: "The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system." in: Endocrinology, Vol. 150, Issue 11, pp. 5016-26, (2009) (PubMed).

Castellano, Navarro, Fernández-Fernández, Roa, Vigo, Pineda, Dieguez, Aguilar, Pinilla, Tena-Sempere: "Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats." in: Diabetes, Vol. 55, Issue 9, pp. 2602-10, (2006) (PubMed).

Schubring, Prohaska, Prohaska, Englaro, Blum, Siebler, Kratzsch, Kiess: "Leptin concentrations in maternal serum and amniotic fluid during the second trimenon: differential relation to fetal gender and maternal morphometry." in: European journal of obstetrics, gynecology, and reproductive biology, Vol. 86, Issue 2, pp. 151-7, (1999) (PubMed).

Gong, Bi, Pratley, Weintraub: "Genomic structure and promoter analysis of the human obese gene." in: The Journal of biological chemistry, Vol. 271, Issue 8, pp. 3971-4, (1996) (PubMed).

Masuzaki, Ogawa, Isse, Satoh, Okazaki, Shigemoto, Mori, Tamura, Hosoda, Yoshimasa: "Human obese gene expression. Adipocyte-specific expression and regional differences in the adipose tissue." in: Diabetes, Vol. 44, Issue 7, pp. 855-8, (1995) (PubMed).

Aliases for Leptin Proteins

leptin (Lep) Proteins
leptin (LEP) Proteins
leptin (lep) Proteins
LEPD Proteins
ob Proteins
OB Proteins
obese Proteins
OBS Proteins
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