KCNJ1 Products
(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))
Categories
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured KCNJ1 Categories
KCNJ1 Antibodies
High quality antibodies with extensive validation data.
KCNJ1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KCNJ1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN7264605
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7145017
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IF
Validations
- (2)
Cat. No.
ABIN7145013
Quantity
100 μg
Datasheet
Datasheet
Recommended KCNJ1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6210712
Quantity
96 tests
Datasheet
Datasheet
Recommended KCNJ1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308433
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1780435
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3082421
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our KCNJ1 products
: "Hydronephrosis is associated with elevated plasmin in urine in pediatric patients and rats and changes in NCC and γ-ENaC abundance in rat kidney." in: American journal of physiology. Renal physiology, Vol. 315, Issue 3, pp. F547-F557, (2018) (PubMed).: "WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 35, pp. 14366-71, (2013) (PubMed).
: "Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel." in: Molecular pharmacology, Vol. 79, Issue 1, pp. 42-50, (2010) (PubMed).
: "Common variants in genes underlying monogenic hypertension and hypotension and blood pressure in the general population." in: Hypertension, Vol. 51, Issue 6, pp. 1658-64, (2008) (PubMed).
: "Rare independent mutations in renal salt handling genes contribute to blood pressure variation." in: Nature genetics, Vol. 40, Issue 5, pp. 592-9, (2008) (PubMed).
Synonyms and alternative names related to KCNJ1
potassium voltage-gated channel subfamily J member 1 (KCNJ1), potassium voltage-gated channel subfamily J member 1 L homeolog (kcnj1.L), potassium voltage-gated channel subfamily J member 1 (kcnj1), potassium voltage-gated channel subfamily J member 1 (Kcnj1), potassium inwardly-rectifying channel, subfamily J, member 1 (Kcnj1), potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 (kcnj1a.1), Kcnj, kcnj1, KIR1.1, kir1.1, Kir1.1, ROMK, ROMK1, romk1, Romk2, wu:fl37c05, zgc:63534Protein level used designations for KCNJ1
- ATP-regulated potassium channel ROM-K
- ATP-sensitive inward rectifier potassium channel 1
- inward rectifier K(+) channel Kir1.1
- inwardly rectifying K+ channel
- potassium channel, inwardly rectifying subfamily J member 1
- potassium inwardly-rectifying channel, subfamily J, member 1
- potassium inwardly-rectifying channel J1
- ATP-sensitive inward rectifier potassium channel 1-like
- K+ channel protein
- KAB-1
- Potassium inwardly-rectifying channel subfamily J
- kir1.1
- inwardly rectifying potassium channel ROMK-2
- LOW QUALITY PROTEIN: ATP-sensitive inward rectifier potassium channel 1
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