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Keratin 86 Products

(Keratin 86 (KRT86))
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle\; this hair keratin, as well as KRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutations in this gene and KRTHB1 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008].

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Featured Keratin 86 Categories

Keratin 86 Antibodies

High quality antibodies with extensive validation data.

Keratin 86 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Keratin 86 Antibodies

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Reactivity Human
Application WB
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Cat. No. ABIN6389659
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Cat. No. ABIN2451443
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Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3121268
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Latest Publications for our Keratin 86 products

ZHANG, MENG, ZHAO, TIAN: "Mutation E402K of the hHb6 in a Chinese Han family with monilethrix." in: European journal of dermatology : EJD, Vol. 19, Issue 5, pp. 508-9, (2009) (PubMed).

Feng, Liu, Yang: "[Analysis of human hair basic keratin 6 gene mutation in a Chinese Han family with monilethrix]." in: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, Vol. 25, Issue 2, pp. 141-4, (2008) (PubMed).

Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

Schweizer, Bowden, Coulombe, Langbein, Lane, Magin, Maltais, Omary, Parry, Rogers, Wright: "New consensus nomenclature for mammalian keratins." in: The Journal of cell biology, Vol. 174, Issue 2, pp. 169-74, (2006) (PubMed).

Synonyms and alternative names related to Keratin 86

keratin 86 (Krt86), keratin 86 (KRT86), hair keratin type II intermediate filament (KRT2.11), 5430421N21Rik, AI325212, Hb1, HB6, hHb6, Kb26, Khb4, Krt2-10, Krt2-11, KRT86, KRTHB1, KRTHB6, MHb4, MNX

Protein level used designations for Keratin 86

  • keratin, type II cuticular Hb6
  • type II keratin Kb26
  • keratin 86
  • hair keratin type II intermediate filament
  • K86
  • hair keratin K2.11
  • hard keratin, type II, 6
  • keratin protein HB6
  • keratin, hair, basic, 6 (monilethrix)
  • keratin-86
  • type II hair keratin Hb6
  • type-II keratin Kb26
  • keratin complex 2, basic, gene 10
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